Neural functioning and plasticity can be studied on different levels of organization and
complexity ranging from the molecular and synaptic level to neural circuitry of whole brain …

While functional MRI (fMRI) localizes brain activation and deactivation, functional MRS
(fMRS) provides insights into the underlying metabolic conditions. There is much interest in …

Several studies have attributed certain visual perceptual alterations in older adults to a likely
decrease in GABA (Gamma Aminobutyric Acid) concentration in visual cortex, an …

The aim of this guideline is to provide a series of evidence-based recommendations that
allow those new to using MEGA-PRESS to produce high-quality data for the measurement of …

Spectral editing allows direct measurement of low-concentration metabolites, such as GABA,
glutathione (GSH) and lactate (Lac), relevant for understanding brain (patho) physiology …

Functional magnetic resonance spectroscopy (fMRS) has been used to assess the dynamic
metabolic responses of the brain to a physiological stimulus non-invasively. However, only …

Balance between inhibitory and excitatory neurotransmitter systems and the protective role
of the major antioxidant glutathione (GSH) are central to early healthy brain development …

Purpose To demonstrate the framework of a novel Hadamard-encoded spectral editing
approach for simultaneously detecting multiple low-concentration brain metabolites in vivo …

BACKGROUND AND PURPOSE: Gamma-aminobutyric acid (GABA) is the primary inhibitory
neurotransmitter in the human brain and is implicated in several neuropathologies …

Recent advances in J-difference-edited proton magnetic resonance spectroscopy (1 H MRS)
data acquisition and processing have led to the development of Hadamard Encoding and …