Diverse macrophage populations contribute to distinct manifestations of human cutaneous graft-versus-host disease

J Strobl, LM Gail, L Krecu, S Madad… - British Journal of …, 2024 - academic.oup.com
Background Graft-versus-host disease (GvHD) is a major life-threatening complication of
allogeneic haematopoietic stem cell transplantation (HSCT), limiting the broad application of …

[HTML][HTML] Insights from integrating clinical and preclinical studies advance understanding of graft-versus-host disease

G Socié, LS Kean, R Zeiser… - The Journal of clinical …, 2021 - Am Soc Clin Investig
As a result of impressive increases in our knowledge of rodent and human immunology, the
understanding of the pathophysiologic mechanisms underlying graft-versus-host disease …

[HTML][HTML] Complex interactions of cellular players in chronic Graft-versus-Host Disease

LM Gail, KJ Schell, P Łacina, J Strobl… - Frontiers in …, 2023 - frontiersin.org
Chronic Graft-versus-Host Disease is a life-threatening inflammatory condition that affects
many patients after allogeneic hematopoietic stem cell transplantation. Although we have …

Antibiotic use and ileocolonic immune cells in patients receiving fecal microbiota transplantation for refractory intestinal GvHD: a prospective cohort study

W Spindelboeck, B Halwachs, N Bayer… - Therapeutic …, 2021 - journals.sagepub.com
Introduction: Treatment-refractory, acute graft-versus-host disease (GvHD) of the lower
gastrointestinal tract (GI) after allogeneic hematopoietic stem cell transplantation is life …

Advancements in the characterization of tissue resident memory T cells in skin disease

L Li, PP Liu, C Chen, B Yan, X Chen, J Li, C Peng - Clinical Immunology, 2022 - Elsevier
The newly discovered subset of memory T cells, tissue resident memory T (TRM) cells,
reside in peripheral tissues for a long time, contributing to a rapid immune response and …

[HTML][HTML] Accumulation of cytotoxic skin resident memory T cells and increased expression of IL-15 in lesional skin of polymorphic light eruption

VK Patra, J Strobl, D Atzmüller, B Reininger… - Frontiers in …, 2022 - frontiersin.org
Patients with polymorphic light eruption (PLE) develop lesions upon the first exposure to sun
in spring/summer, but lesions usually subside during season due to the natural (or medical) …

[HTML][HTML] Milestones in acute GVHD pathophysiology

G Socie, D Michonneau - Frontiers in Immunology, 2022 - frontiersin.org
In the past 65 years, over 25 000 referenced articles have been published on graft-versus-
host disease (GVHD). Although this included clinically orientated papers or publications on …

Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer

N Bayer, B Hausmann, RV Pandey, F Deckert, LM Gail… - Leukemia, 2022 - nature.com
The composition of the gut microbiome influences the clinical course after allogeneic
hematopoietic stem cell transplantation (HSCT), but little is known about the relevance of …

T‐cell memory in tissues

KPJM van Gisbergen, KD Zens… - European journal of …, 2021 - Wiley Online Library
Immunological memory equips our immune system to respond faster and more effectively
against reinfections. This acquired immunity was originally attributed to long‐lived, memory …

Memory T cells in the immunoprevention of cancer: a switch from therapeutic to prophylactic approaches

S Mittra, SM Harding, SM Kaech - The Journal of Immunology, 2023 - journals.aai.org
Cancer immunoprevention, the engagement of the immune system to prevent cancer, is
largely overshadowed by therapeutic approaches to treating cancer after detection …