Angiotensin converting enzyme inhibitors: comparative structure, pharmacokinetics, and pharmacodynamics

GS Thind - Cardiovascular drugs and therapy, 1990 - Springer
Angiotensin converting enzyme (ACE) inhibitors are a novel class of antihypertensive and
anticongestive heart failure agents with wide patient and physician acceptability. By blocking …

Quinapril: a review of its pharmacological properties, and therapeutic efficacy in cardiovascular disorders

AN Wadworth, RN Brogden - Drugs, 1991 - Springer
Synopsis Quinapril is a monoethyl ester which is hydrolysed after absorption to form an
active metabolite, quinaprilat, which is a more potent angiotensin converting enzyme (ACE) …

Transport of temocaprilat into rat hepatocytes: role of organic anion transporting polypeptide

H Ishizuka, K Konno, H Naganuma, K Nishimura… - … of Pharmacology and …, 1998 - ASPET
The mechanism for hepatic uptake of temocaprilat, an angiotensin-converting enzyme
inhibitor that is predominantly excreted into bile was studied using isolated rat hepatocytes …

Management of heart failure: I. Pharmacologic treatment

DW Baker, MA Konstam, M Bottorff, B Pitt - JAMA, 1994 - jamanetwork.com
Objective.—This review of the pharmacologic treatment of heart failure due to left ventricular
systolic dysfunction summarizes the recommendations of the expert panel for the Agency for …

Rapid improvement of acute pulmonary edema with sublingual captopril

RJ Hamilton, WA Carter… - Academic Emergency …, 1996 - Wiley Online Library
Objective: To test the hypothesis that sublingual captopril produces a more rapid
improvement of acute pulmonary edema (APE) than does placebo, when added to a …

Perindopril: a review of its pharmacokinetics and clinical pharmacology

RJ Macfadyen, KR Lees, JL Reid - Drugs, 1990 - Springer
Perindopril is an orally active, non-thiol angiotensin-converting enzyme (ACE) inhibitor,
which in doses of 4 to 8mg is effective in the control of essential hypertension. As …

Pharmacokinetics of intravenously and orally administered eprosartan in healthy males: absolute bioavailability and effect of food

D Tenero, D Martin, B Ilson… - … & drug disposition, 1998 - Wiley Online Library
Eighteen healthy males received a single 300 mg oral dose of eprosartan as the commercial
wet granulation formulation under fasting conditions and following a high‐fat breakfast and a …

Detecting the adulteration of antihypertensive health food using G-insertion enhanced fluorescent DNA-AgNCs

Y Guo, Y Zhang, R Pei, Y Cheng, Y Xie, H Yu… - Sensors and Actuators B …, 2019 - Elsevier
In this work, a new phenomenon was found that the insertion of guanine (G) bases into the
cytosine (C)-rich DNA could endow enhanced fluorescence intensity of DNA-templated …

[HTML][HTML] Estudo termoanalítico de comprimidos revestidos contendo captopril através de termogravimetria (TG) e calorimetria exploratória diferencial (DSC)

GC Bazzo, MAS Silva - Revista Brasileira de Ciências Farmacêuticas, 2005 - SciELO Brasil
No presente trabalho foram desenvolvidos comprimidos de captopril revestidos com
hidroxipropilmetilcelulose (HPMC), Opadry®, polivinilpirrolidona (PVP), Eudragit® E e goma …

Mechanism and functional substances of Saiga antelope horn in treating hypertension with liver-yang hyperactivity syndrome explored using network pharmacology …

W Wu, R Liu, S Guo, W Song, Y Hua, M Hong… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Saiga antelope horn (SAH) is a traditional Chinese
medicine for treating hypertension with liver-yang hyperactivity syndrome (Gan-Yang-Shang …