Experimental animal models for diabetes and its related complications—a review
CPD Kottaisamy, DS Raj, V Prasanth Kumar… - Laboratory animal …, 2021 - Springer
Diabetes mellitus, a very common and multifaceted metabolic disorder is considered as one
of the fastest growing public health problems in the world. It is characterized by …
of the fastest growing public health problems in the world. It is characterized by …
Fibrosis of the diabetic heart: Clinical significance, molecular mechanisms, and therapeutic opportunities
I Tuleta, NG Frangogiannis - Advanced drug delivery reviews, 2021 - Elsevier
In patients with diabetes, myocardial fibrosis may contribute to the pathogenesis of heart
failure and arrhythmogenesis, increasing ventricular stiffness and delaying conduction …
failure and arrhythmogenesis, increasing ventricular stiffness and delaying conduction …
Antidiabetic activity of avocado seeds (Persea americana Mill.) in diabetic rats via activation of PI3K/AKT signaling pathway
OA Ojo, JC Amanze, AI Oni, S Grant, M Iyobhebhe… - Scientific reports, 2022 - nature.com
The treatment of diabetes involves the use of herbal plants, attracting interest in their cost-
effectiveness and efficacy. An aqueous extract of Persea americana seeds (AEPAS) was …
effectiveness and efficacy. An aqueous extract of Persea americana seeds (AEPAS) was …
Efficacy of caffeic acid on diabetes and its complications in the mouse
Diabetic dyslipidemia and hyperglycemia contribute to excessive reactive oxygen species
(ROS) production, leading to deleterious complications, such as nephropathy …
(ROS) production, leading to deleterious complications, such as nephropathy …
Effects of vernonia amygdalina fractionate on glutathione reductase and glutathione-S-transferase on alloxan induced diabetes wistar rat
Abstracts This research was conducted to examine the effect of vernonia amygdalina on
Glutathione reductase and Glutathione-S-transferase in alloxan induced diabetic wistar rats …
Glutathione reductase and Glutathione-S-transferase in alloxan induced diabetic wistar rats …
[HTML][HTML] Biological and bioactive components of bitter leaf (Vernonia amygdalina leaf): insight on health and nutritional benefits. A review
GI Edo, PO Samuel, AN Jikah, FO Onoharigho… - Food Chemistry …, 2023 - Elsevier
Recently, significant attention has been paid to the biologically active substances in plants
that aid in preventing, treating or delaying diseases brought on by inflammatory and …
that aid in preventing, treating or delaying diseases brought on by inflammatory and …
[HTML][HTML] Phytochemical profile and antioxidant capacity, α-amylase and α-glucosidase inhibitory activities of Oxalis pes-caprae extracts in alloxan-induced diabetic …
Diabetes and its complications are closely correlated with chronic hyperglycemia, causing
severe oxidative stress and leading to glycation reaction with formation of advanced …
severe oxidative stress and leading to glycation reaction with formation of advanced …
Preclinical models for Alzheimer's disease: past, present, and future approaches
A robust preclinical disease model is a primary requirement to understand the underlying
mechanisms, signaling pathways, and drug screening for human diseases. Although various …
mechanisms, signaling pathways, and drug screening for human diseases. Although various …
[HTML][HTML] α-glucosidase inhibitory, antioxidant activity, and GC/MS analysis of Descurainia sophia methanolic extract: In vitro, in vivo, and in silico studies
M Sadeghi, MS Khomartash… - Arabian journal of …, 2022 - Elsevier
Due to the presence of various phenolic compounds in D. sophia, this plant may have an
inhibitory effect on α-Glc and ultimately diabetes control. Therefore, this work aims to …
inhibitory effect on α-Glc and ultimately diabetes control. Therefore, this work aims to …
[PDF][PDF] Effects of paraquat dichloride on adult male wistar rat. an approach in the toxicity of body weights and hematological tissues
GI Edo - J Anal Pharm Res, 2022 - pdfs.semanticscholar.org
The main objective of the experiment is aimed to examine the impact of paraquat dichloride
on the body weights of adult male Wistar rats as well as in their haematological tissues. The …
on the body weights of adult male Wistar rats as well as in their haematological tissues. The …