Chronic spinal cord injury (SCI) is a devastating condition that results in major neurological
deficits and social burden. It continues to be managed symptomatically, and no real …

Spinal cord injury (SCI) is an injurious process that begins with immediate physical damage
to the spinal cord and associated tissues during an acute traumatic event. However, the …

The stem cell-based experimental therapies are partially successful for the recovery of
spinal cord injury (SCI). Recently, acellular spinal cord (ASC) scaffolds which mimic native …

The extracellular matrix (ECM) is an active and complex microenvironment with outstanding
biomechanical, biophysical, and biochemical characteristics, which can indirectly or directly …

Spinal cord injury (SCI) is a common, severe damage to the central nervous system. Here,
we discuss the use of biomaterials for stem cell transplantation in preclinical and clinical …

Bone marrow-derived mesenchymal stem cells (BM-MSCs) play a crucial role in stem cell
therapy and are extensively used in regenerative medicine research. However, current …

OBJECTIVE There is controversy about the role of scaffolds as an adjunctive therapy to
mesenchymal stem cell (MSC) transplantation in spinal cord injury (SCI). Thus, the authors …

The role of regenerative medicine in clinical therapies is becoming increasingly vital. Under
specific conditions, mesenchymal stem cells (MSCs) are capable of differentiating into …

The architecture and mechanical properties of a scaffold for spinal cord injury treatment must
provide tissue integration as well as effective axonal regeneration. Previous work has …

Spinal cord injury triggers a complex set of events that lead to tissue healing without the
restoration of normal function due to the poor regenerative capacity of the spinal cord …