Background Heart failure (HF) is a significant cause of mortality in children and therefore
there is interest in understanding the optimal way to support these children with Ventricular …

Despite the development of catheter‐based interventions for ischemic and valvular heart
disease, hundreds of thousands of people undergo open heart surgery annually for …

Thrombotic and bleeding complications have historically been major causes of morbidity
and mortality in pediatric ventricular assist device (VAD) support. Standard anticoagulation …

The Institute for Healthcare Improvement's Model coupled with existing evidence and expert
opinion were used to identify care processes likely to affect stroke rates. These care …

The evolution of devices for mechanical circulatory support (MCS), including ventricular
assist devices (VADs) for patients with heart failure and extracorporeal membrane …

Background Research evaluating hemostatic agents for the treatment of clinically significant
bleeding has been hampered by inconsistency and lack of standardized primary clinical trial …

Heart failure is a significant cause of mortality in children with cardiovascular diseases.
Treatment of heart failure depends on patients' symptoms, age, and severity of their …

Background Learning networks have emerged in medicine as a novel organizational
structure that contains elements of quality improvement, education, and research with the …

Ventricular assist devices (VAD) are used more in children. Safe and effective
anticoagulation is required for successful management of children supported with ventricular …

Bivalirudin has been used in increasing frequency as an alternative to unfractionated
heparin (UFH) in pediatric recipients of Berlin Heart EXCOR ventricular assist devices …