Importance Observational (nonexperimental) studies that aim to emulate a randomized trial
(ie, the target trial) are increasingly informing medical and policy decision-making, but it is …

COVID pneumonitis can cause patients to become critically ill. They may require intensive
care and mechanical ventilation. Ventilator-associated pneumonia (VAP) is a concern. This …

Background A significant proportion of Coronavirus Disease 2019 (COVID-19) patients
require admission to the intensive care unit (ICU) and invasive mechanical ventilation (IMV) …

Background The association of tracheostomy timing and clinical outcomes in ventilated
COVID-19 patients remains controversial. We performed a meta-analysis to evaluate the …

Many of the patients with COVID-19 have suffered respiratory distress requiring prolonged
endotracheal intubation (ETI) resulting in laryngotracheal complication with an impact on …

Résumé La pneumopathie à COVID-19 présente plusieurs particularités dans sa
présentation clinique (orage cytokinique, hypoxémie silencieuse, risque thromboembolique) …

Objective: To determine the effect of timing of tracheotomy on the outcome of critically-ill
elderly patients. Study Design: Descriptive study. Place and Duration of the Study: Intensive …

Since the beginning of the COVID-19 pandemic, setting of mechanical ventilation in critically
ill patients with COVID-19 associated acute respiratory distress syndrome (C-ARDS) has …

To the Editor: I read with interest a study by Hernández et al 1 published in CHEST (January
2022). Therein, the authors present a retrospective cohort study that examined outcomes …

Background The role of early tracheostomy as an intervention for critically ill COVID‐19
patients is unclear. Previous reports have described prolonged intensive care stays and …