Rising incidence of early-onset colorectal cancer—A call to action

N Akimoto, T Ugai, R Zhong, T Hamada… - Nature reviews Clinical …, 2021 - nature.com
The incidence of early-onset colorectal cancer (CRC), which occurs in individuals< 50 years
of age, has been increasing worldwide and particularly in high-income countries. The …

[HTML][HTML] Exosomes as potential sources of biomarkers in colorectal cancer

Y Xiao, J Zhong, B Zhong, J Huang, L Jiang, Y Jiang… - Cancer letters, 2020 - Elsevier
Colorectal cancer (CRC), a common malignancy, is among the leading causes of cancer-
related deaths worldwide. Developing novel biomarkers is an important public health …

Global patterns and trends in colorectal cancer incidence in young adults

RL Siegel, LA Torre, I Soerjomataram, RB Hayes… - Gut, 2019 - gut.bmj.com
Objective Early-onset colorectal cancer (CRC) is increasing in the USA despite rapid
declines in older ages. Similar patterns are reported in Australia and Canada, but a …

Western-style diet, pks island-carrying Escherichia coli, and colorectal cancer: analyses from two large prospective cohort studies

K Arima, R Zhong, T Ugai, M Zhao, K Haruki, N Akimoto… - Gastroenterology, 2022 - Elsevier
Background & Aims Evidence supports a carcinogenic role of Escherichia coli carrying the
pks island that encodes enzymes for colibactin biosynthesis. We hypothesized that the …

Radiomics and machine learning analysis based on magnetic resonance imaging in the assessment of liver mucinous colorectal metastases

V Granata, R Fusco, F De Muzio, C Cutolo… - La radiologia …, 2022 - Springer
Purpose The purpose of this study is to evaluate the Radiomics and Machine Learning
Analysis based on MRI in the assessment of Liver Mucinous Colorectal Metastases. Query …

[HTML][HTML] Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts

JA Rothwell, J Bešević, N Dimou, M Breeur, N Murphy… - BMC medicine, 2023 - Springer
Background Amino acid metabolism is dysregulated in colorectal cancer patients; however,
it is not clear whether pre-diagnostic levels of amino acids are associated with subsequent …

The microbiome, genetics, and gastrointestinal neoplasms: the evolving field of molecular pathological epidemiology to analyze the tumor–immune–microbiome …

K Mima, K Kosumi, Y Baba, T Hamada, H Baba… - Human genetics, 2021 - Springer
Metagenomic studies using next-generation sequencing technologies have revealed rich
human intestinal microbiome, which likely influence host immunity and health conditions …

Lipid–Polymer Hybrid Nanoparticles with Both PD-L1 Knockdown and Mild Photothermal Effect for Tumor Photothermal Immunotherapy

D Chuan, R Fan, B Chen, Y Ren, M Mu… - … Applied Materials & …, 2023 - ACS Publications
In developing countries, the incidence of colorectal cancer (CRC) is on the rise. The
combination of programmed cell death ligand-1 (PD-L1) siRNA (siPD-L1) and mild …

Colorectal cancer incidence, mortality, tumour characteristics, and treatment before and after introduction of the faecal immunochemical testing-based screening …

ECH Breekveldt, I Lansdorp-Vogelaar… - The lancet …, 2022 - thelancet.com
Background In 2014, a population-based colorectal cancer (CRC) screening programme
was stepwise implemented in the Netherlands comprising faecal immunochemical testing …

[HTML][HTML] Radiomics and machine learning analysis based on magnetic resonance imaging in the assessment of colorectal liver metastases growth pattern

V Granata, R Fusco, F De Muzio, C Cutolo… - Diagnostics, 2022 - mdpi.com
To assess Radiomics and Machine Learning Analysis in Liver Colon and Rectal Cancer
Metastases (CRLM) Growth Pattern, we evaluated, retrospectively, a training set of 51 …