Pharmacology of dipeptidyl peptidase-4 inhibitors and its use in the management of metabolic syndrome: a comprehensive review on drug repositioning

M Rameshrad, BM Razavi, GAA Ferns… - DARU Journal of …, 2019 - Springer
Objectives Despite advances in our understanding of metabolic syndrome (MetS) and the
treatment of each of its components separately, currently there is no single therapy approved …

Cardiovascular effects of anti-diabetes drugs

LM Younk, EM Lamos, SN Davis - Expert opinion on drug safety, 2016 - Taylor & Francis
Introduction: Cardiovascular disease remains the major contributor to morbidity and mortality
in diabetes. From the need to reduce cardiovascular risk in diabetes and to ensure that such …

Effect of vildagliptin versus glibenclamide on endothelial function and arterial stiffness in patients with type 2 diabetes and hypertension: a randomized controlled trial

LN Cosenso-Martin, LT Giollo-Júnior, LAB Fernandes… - Acta …, 2018 - Springer
Aims Several trials have reported that dipeptidyl peptidase-4 (DPP-4) inhibitors, used to treat
type 2 diabetes (T2DM), improve endothelial function. The current study investigated the …

Randomized study comparing vildagliptin vs glibenclamide on glucose variability and endothelial function in patients with type 2 diabetes mellitus and hypertension

LN Cosenso-Martin, LY Takaoka… - … Syndrome and Obesity, 2020 - Taylor & Francis
Background Glucose variability (GV) is considered an important factor for cardiovascular
disease (CVD) in patients with type 2 diabetes mellitus (T2DM). High GV causes endothelial …

Efficacy and Safety of Single‐or Double‐Drug Antidiabetic Regimens in the Treatment of Type 2 Diabetes Mellitus: A Network Meta‐Analysis

XL Yang, MM Duo‐Ji, ZW Long - Journal of Cellular …, 2017 - Wiley Online Library
ABSTRACT A network meta‐analysis was performed in order to compare the efficacy and
safety of single‐or double‐drug antidiabetic regimens in the treatment of type 2 diabetes …

[PDF][PDF] Место ингибиторов ДПП-4 в диабетологической практике

ЛГ Полозова - Проблеми ендокринної патології, 2018 - irbis-nbuv.gov.ua
Так, ранее приоритеты при назначении сахароснижающих препаратов отдавались
применению сенситайзерам к инсулину. А в настоящий момент фокус современного …

Utility of Invasive and Non-invasive Cardiovascular Research Methodologies in Drug Development for Diabetes, Obesity and NAFLD/NASH

G Rodriguez-Araujo, AJ Krentz - … , and Nonalcoholic Fatty Liver Disease: A …, 2019 - Springer
Mechanistic intersections between metabolic and cardiovascular disorders are increasingly
appreciated. Novel pharmacotherapies for diabetes and obesity that may simultaneously …

[PDF][PDF] Randomized Study Comparing Vildagliptin vs Glibenclamide on Glucose Variability and Endothelial Function in Patients with Type 2 Diabetes Mellitus and …

LY Takaoka, JF Vilela-Martin - researchgate.net
Background: Glucose variability (GV) is considered an important factor for cardiovascular
disease (CVD) in patients with type 2 diabetes mellitus (T2DM). High GV causes endothelial …

[PDF][PDF] EXPERIENCE OF VILDAGLIPTIN USE IN VARIOUS CLINICAL SITUATIONS

OS Orlyk - Problems of Endocrine Pathology, 2019 - ojs.endocrinology.org.ua
ДОСВ²Д ЗАСТОСУВАННЯ В²ЛДАГЛ²ПТИНУ В Р²ЗНИХ КЛ²Н²ЧНИХ СИТУАЦ²ЯХ* Page 1 81
Проблеми ендокринної патології № 4, 2019 ISSN 2518-1432 (Online); ISSN 2227-4782 (Print) …

The role of DPP-4 inhibitors in diabetological care

LG Polozova - Problems of Endocrine Pathology, 2018 - jpep.endocrinology.org.ua
Diabetes mellitus type 2 is the most important medical problem in many countries within the
world. The features of hypoglycemic drug with high efficiency include the effectivity, safety …