Role of estrogen receptors in health and disease

P Chen, B Li, L Ou-Yang - Frontiers in endocrinology, 2022 - frontiersin.org
Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …

An overview of PROTACs: a promising drug discovery paradigm

Z Liu, M Hu, Y Yang, C Du, H Zhou, C Liu, Y Chen… - Molecular …, 2022 - Springer
Proteolysis targeting chimeras (PROTACs) technology has emerged as a novel therapeutic
paradigm in recent years. PROTACs are heterobifunctional molecules that degrade target …

Endocrine role of bone in the regulation of energy metabolism

R Zhou, Q Guo, Y Xiao, Q Guo, Y Huang, C Li, X Luo - Bone research, 2021 - nature.com
Abstracts Bone mainly functions as a supportive framework for the whole body and is the
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …

Neurodegenerative disease: roles for sex, hormones, and oxidative stress

N Sumien, JT Cunningham, DL Davis… - …, 2021 - academic.oup.com
Neurodegenerative diseases cause severe impairments in cognitive and motor function.
With an increasing aging population and the onset of these diseases between 50 and 70 …

Oestrogenic endocrine disruptors in the placenta and the fetus

ZR Tang, XL Xu, SL Deng, ZX Lian, K Yu - International journal of …, 2020 - mdpi.com
Endocrine disrupting chemicals (EDCs) are exogenous substances that interfere with the
stability and regulation of the endocrine system of the body or its offspring. These …

Botanicals and their bioactive phytochemicals for women's health

BM Dietz, A Hajirahimkhan, TL Dunlap… - Pharmacological reviews, 2016 - ASPET
Botanical dietary supplements are increasingly popular for women's health, particularly for
older women. The specific botanicals women take vary as a function of age. Younger …

Resveratrol: An overview of its anti-cancer mechanisms

M Elshaer, Y Chen, XJ Wang, X Tang - Life sciences, 2018 - Elsevier
Cancer is one of the leading causes of death worldwide. Chemotherapy and radiotherapy
are the conventional primary treatments for cancer patients. However, most of cancer cells …

Estrogen-receptor expression and function in female reproductive disease

ZR Tang, R Zhang, ZX Lian, SL Deng, K Yu - Cells, 2019 - mdpi.com
Estrogen receptors (ER) include ER alpha, ER beta and new membrane receptor G protein-
coupled receptor 30 (GPR30). Estrogen receptors are key receptors to maintain ovarian …

Functions of the aryl hydrocarbon receptor (AHR) beyond the canonical AHR/ARNT signaling pathway

NC Sondermann, S Faßbender, F Hartung… - Biochemical …, 2023 - Elsevier
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor regulating
adaptive and maladaptive responses toward exogenous and endogenous signals …

Guía de práctica clínica de la Sociedad Interamericana de Cardiología sobre prevención primaria de enfermedad cardiovascular en la mujer

MA Sueldo, MAM Rivera… - … de cardiología de …, 2022 - scielo.org.mx
Guía de práctica clínica de la Sociedad Interamericana de Cardiología sobre prevención
primaria de enfermedad cardiovascular en la mujer SciELO - Scientific Electronic Library …