Protein glycosylation is one of the most common and important post-translational
modifications of proteins involved in regulating glycoprotein functions. The chemoenzymatic …

As a vital project of forward chemical genetic research, target deconvolution aims to identify
the molecular targets of an active hit compound. Chemoproteomics, either with chemical …

Core fucosylation and O-GlcNAcylation are the two most famous protein glycosylation
modifications that regulate diverse physiological and pathological processes in living …

Core fucosylation, a special type of N-linked glycosylation, is important in tumor proliferation,
invasion, metastatic potential, and therapy resistance. However, the core-fucosylated …

Structure-defined N-glycans are essential tools to uncover the molecular basis of N-glycan
functions. However, the difficulty in obtaining diverse collections of well-defined N-glycans …

Dysregulation of protein core-fucosylation plays a pivotal role in the onset, progression, and
immunosuppression of cancer. However, analyzing core-fucosylation, especially the …