Targeting transcription factors for therapeutic benefit in rheumatoid arthritis
T Balendran, K Lim, JA Hamilton… - Frontiers in …, 2023 - frontiersin.org
Rheumatoid arthritis (RA) is a destructive inflammatory autoimmune disease that causes
pain and disability. Many of the currently available drugs for treating RA patients are aimed …
pain and disability. Many of the currently available drugs for treating RA patients are aimed …
[HTML][HTML] Ugonin P inhibits lung cancer motility by suppressing DPP-4 expression via promoting the synthesis of miR-130b-5p
Lung cancer is the leading cause of cancer-related death worldwide, and the survival rate of
metastatic lung cancer is exceedingly low. Helminthostatchys Zeylanica (H. Zeylanica) is a …
metastatic lung cancer is exceedingly low. Helminthostatchys Zeylanica (H. Zeylanica) is a …
[HTML][HTML] Hypoxia-regulated exosomes mediate M2 macrophage polarization and promote metastasis in chondrosarcoma
Chondrosarcoma is a primary malignant bone tumor. Traditional therapy is not very effective,
and it is prone to metastasis in the late stage. The tumor microenvironment (TME) plays a …
and it is prone to metastasis in the late stage. The tumor microenvironment (TME) plays a …
A combination of isoliquiritigenin with Artemisia argyi and Ohwia caudata water extracts attenuates oxidative stress, inflammation, and apoptosis by modulating Nrf2 …
Abstract Ohwia caudata (Thunb.) H. Ohashi (Leguminosae) also called as “Evergreen
shrub” and Artemisia argyi H. Lév. and Vaniot (Compositae) also named as “Chinese …
shrub” and Artemisia argyi H. Lév. and Vaniot (Compositae) also named as “Chinese …
Ohwia caudata aqueous extract attenuates doxorubicin‐induced mitochondrial dysfunction in Wharton's jelly‐derived mesenchymal stem cells
PY Lee, BCK Tsai, MA Sitorus, PY Lin… - Environmental …, 2023 - Wiley Online Library
Mitochondrial dysfunction has been linked to many diseases, including organ degeneration
and cancer. Wharton's jelly‐derived mesenchymal stem cells provide a valuable source for …
and cancer. Wharton's jelly‐derived mesenchymal stem cells provide a valuable source for …
Nanocomposite hydrogel to deliver the immunomodulator lenalidomide and anti-inflammatory hesperidin locally to joints affected by rheumatoid arthritis
X Du, Y Lin, Z Shuai, J Duan, C Wang, J Liu… - Chemical Engineering …, 2023 - Elsevier
Rheumatoid arthritis is an autoimmune disease characterized by inflammatory cell
infiltration, neovascularization in the synovial tissue, and progressive joint destruction. The …
infiltration, neovascularization in the synovial tissue, and progressive joint destruction. The …
Folic Acid and Folinic Acid Protect Hearts of Aging Triple-transgenic Alzheimer's Disease mice via IGF1R/PI3K/AKT and SIRT1/AMPK Pathways
DT Ju, RFS Huang, BCK Tsai, YC Su, PL Chiu… - Neurotoxicity …, 2023 - Springer
Patients with Alzheimer's disease have increased risk of developing heart disease, which
therefore highlights the need for strategies aiming at reducing Alzheimer's disease-related …
therefore highlights the need for strategies aiming at reducing Alzheimer's disease-related …
Platycodi radix aqueous extract salvages doxorubicin‐induced senescence by mitochondrial reactive oxygen species reduction in umbilical cord matrix stem cells
PY Lee, MA Sitorus, CH Kuo, BCK Tsai… - Environmental …, 2024 - Wiley Online Library
Platycodi radix is a widely used herbal medicine that contains numerous phytochemicals
beneficial to health. The health and biological benefits of P. radix have been found across …
beneficial to health. The health and biological benefits of P. radix have been found across …
Anethole mitigates H2O2‐induced inflammation in HIG‐82 synoviocytes by suppressing the aquaporin 1 expression and activating the protein kinase A pathway
TL Huang, YC Chang, BCK Tsai… - Environmental …, 2024 - Wiley Online Library
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease affecting approximately
1% of the global population, with a higher prevalence in women than in men. Chronic …
1% of the global population, with a higher prevalence in women than in men. Chronic …
Angiotensin II prompts heart cell apoptosis via AT1 receptor-augmented phosphatase and tensin homolog and miR-320-3p functions to enhance suppression of the …
SY Lu, WZ Hong, BCK Tsai, YC Chang… - Journal of …, 2022 - journals.lww.com
Background: Hypertension is a severe public health risk factor worldwide. Elevated
angiotensin II (Ang II) produced by the renin–angiotensin–aldosterone system can lead to …
angiotensin II (Ang II) produced by the renin–angiotensin–aldosterone system can lead to …