Drug therapy for osteoporosis in older adults

IR Reid, EO Billington - The Lancet, 2022 - thelancet.com
The goal of osteoporosis management is to prevent fractures. Several pharmacological
agents are available to lower fracture risk, either by reducing bone resorption or by …

Osteoporosis in men

T Vilaca, R Eastell, M Schini - The lancet Diabetes & endocrinology, 2022 - thelancet.com
Osteoporosis in men is a common but often overlooked disorder by clinicians. The criterion
for osteoporosis diagnosis in men is similar to that in women—namely, a bone mineral …

Management of patients at very high risk of osteoporotic fractures through sequential treatments

EM Curtis, JY Reginster, N Al-Daghri, E Biver… - Aging clinical and …, 2022 - Springer
Osteoporosis care has evolved markedly over the last 50 years, such that there are now an
established clinical definition, validated methods of fracture risk assessment and a range of …

Optimising both disease control and glucocorticoid dosing is essential for bone protection in patients with rheumatic disease

E Wiebe, D Huscher, D Schaumburg… - Annals of the …, 2022 - ard.bmj.com
Objectives Inflammatory rheumatic and musculoskeletal diseases (iRMDs) are associated
with increased systemic bone loss that is mediated by chronic inflammation, treatment with …

Novel formulations of oral bisphosphonates in the treatment of osteoporosis

N Fuggle, N Al-Daghri, O Bock, J Branco… - Aging clinical and …, 2022 - Springer
Oral bisphosphonates are a key intervention in the treatment of osteoporosis and in
reducing the risk of fragility fractures. Their use is supported by over 3 decades of evidence; …

Cost effectiveness analyses of interventions for osteoporosis in men: a systematic literature review

N Li, C Beaudart, JA Cauley, SW Ing, NE Lane… - …, 2023 - Springer
Background Osteoporosis is often considered to be a disease of women. Over the last few
years, owing to the increasing clinical and economic burden, the awareness and imperative …

Efficacy of osteoporosis pharmacological treatments in men: a systematic review and meta-analysis

C Beaudart, C Demonceau, S Sabico… - Aging clinical and …, 2023 - Springer
Introduction The objective of this systematic review and meta-analysis is to systematically
identify and review the efficacy of pharmacological treatments in men with osteoporosis …

Development and validation of a feature-based broad-learning system for opportunistic osteoporosis screening using lumbar spine radiographs

B Zhang, Z Chen, R Yan, B Lai, G Wu, J You, X Wu… - Academic …, 2024 - Elsevier
Rationale and Objectives Osteoporosis is primarily diagnosed using dual-energy X-ray
absorptiometry (DXA); yet, DXA is significantly underutilized, causing osteoporosis, an …

Evidence-Based Guideline for the management of osteoporosis in men

NR Fuggle, C Beaudart, O Bruyère… - Nature Reviews …, 2024 - nature.com
Historically, osteoporosis has been viewed as a disease of women, with research, trials of
interventions and guidelines predominantly focused as such. It is apparent, however, that …

Diagnosis of hypogonadism in ageing men

JM Kaufman - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
To make the diagnosis of hypogonadism in an ageing man, in absence of rare organic
cause often referred to as functional or late onset hypogonadism (LOH), he should present …