Background The hepatitis C virus (HCV) is a major public health problem and a leading
cause of chronic liver disease. In the United States, the Centers for Disease Control and …

Recombinant preparations of the cytokine interferon (IFN)-α are increasingly used to treat a
number of medical conditions, including chronic viral hepatitis and several malignancies …

Background The hepatitis C virus (HCV) is a major public health problem and a leading
cause of chronic liver disease. 5 An estimated 180 million people are infected worldwide. 6 …

In high income countries, the majority of new and existing hepatitis C virus (HCV) infections
occur among people who inject drugs (PWID). In many low and middle income countries …

ContextTreatment of chronic hepatitis C virus (HCV) infection in human immunodeficiency
virus (HIV)–infected patients is a growing concern. Most data on the virologic efficacy and …

Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

Mental health problems frequently occur in chronic infection with the hepatitis C virus (HCV)
and during antiviral treatment with pegylated interferon-alpha (PegIFNα) and ribavirin …

Globally,∼ 90% of new hepatitis C infections are attributed to injection drug use, but there is
a continuing reluctance to treat injection drug users (IDUs). There is evidence that a sizeable …

Chronic hepatitis C remains one of the leading causes of chronic liver disease in the United
States, and great emphasis has been placed on treatment of this potentially life-threatening …

The occurrence of depression is higher in patients with chronic liver disease (CLD) than that
in the general population. The mechanism described in previous studies mainly focused on …