Mitochondrial dysfunctions induce PANoptosis and ferroptosis in cerebral ischemia/reperfusion injury: from pathology to therapeutic potential
R She, D Liu, J Liao, G Wang, J Ge… - Frontiers in Cellular …, 2023 - frontiersin.org
Ischemic stroke (IS) accounts for more than 80% of the total stroke, which represents the
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …
leading cause of mortality and disability worldwide. Cerebral ischemia/reperfusion injury …
Targeting ferroptosis with natural products in liver injury: new insights from molecular mechanisms to targeted therapies
Y Liang, S Qiu, Y Zou, L Luo - Phytomedicine, 2023 - Elsevier
Background Ferroptosis is a brand-new type of controlled cell death that is distinguished by
its reliance on iron and the production of lipid peroxidation. The role of ferroptosis in …
its reliance on iron and the production of lipid peroxidation. The role of ferroptosis in …
Natural flavonoids and ferroptosis: Potential therapeutic opportunities for human diseases
Z Zhou, J Li, X Zhang - Journal of Agricultural and Food Chemistry, 2023 - ACS Publications
Flavonoids are a class of bioactive phytochemicals containing a core 2-phenylchromone
skeleton and are widely found in fruits, vegetables, and herbs. Such natural compounds …
skeleton and are widely found in fruits, vegetables, and herbs. Such natural compounds …
Novel insight into the therapeutical potential of flavonoids from traditional Chinese medicine against cerebral ischemia/reperfusion injury
J Zhou, F Sun, W Zhang, Z Feng, Y Yang… - Frontiers in …, 2024 - frontiersin.org
Cerebral ischemia/reperfusion injury (CIRI) is a major contributor to poor prognosis of
ischemic stroke. Flavonoids are a broad family of plant polyphenols which are abundant in …
ischemic stroke. Flavonoids are a broad family of plant polyphenols which are abundant in …
Natural product-derived ferroptosis mediators
YL Chen, LA Xiong, LF Ma, L Fang, ZJ Zhan - Phytochemistry, 2024 - Elsevier
It has been 11 years since ferroptosis, a new mode of programmed cell death, was first
proposed. Natural products are an important source of drug discovery. In the past five years …
proposed. Natural products are an important source of drug discovery. In the past five years …
A panoramic view of ferroptosis in cardiovascular disease
X Cheng, C Yu, X Yang, F Wang, J Min - Kidney Diseases, 2023 - karger.com
Background: Cardiovascular disease (CVD) remains the leading cause of disease burden
worldwide. Ferroptosis, an iron-dependent form of programmed cell death, is characterized …
worldwide. Ferroptosis, an iron-dependent form of programmed cell death, is characterized …
Human umbilical cord mesenchymal stem cell-derived exosomes provide neuroprotection in traumatic brain injury through the lncrna tubb6/nrf2 pathway
L Zhang, W Bai, Y Peng, Y Lin, M Tian - Brain Research, 2024 - Elsevier
Recently, human umbilical cord mesenchymal stem cell (HucMSC) is a new focus of
research in neurological diseases, and the beneficial effect of HucMSC is mediated by …
research in neurological diseases, and the beneficial effect of HucMSC is mediated by …
[HTML][HTML] Ferroptosis: a potential therapeutic target for stroke
C Liu, G Wang, W Han, Q Tian, M Li - Neural Regeneration …, 2024 - journals.lww.com
Ferroptosis is a form of regulated cell death characterized by massive iron accumulation and
iron-dependent lipid peroxidation, differing from apoptosis, necroptosis, and autophagy in …
iron-dependent lipid peroxidation, differing from apoptosis, necroptosis, and autophagy in …
Beyond Mortality: Exploring the Influence of Plant Phenolics on Modulating Ferroptosis—A Systematic Review
N Živanović, M Lesjak, N Simin, SKS Srai - Antioxidants, 2024 - mdpi.com
Ferroptosis is a recently discovered type of programmed cell death that is mechanistically
different from other types of programmed cell death such as apoptosis, necroptosis, and …
different from other types of programmed cell death such as apoptosis, necroptosis, and …
[HTML][HTML] Natural flavonoids act as potent ferroptosis inhibitors and their potentials in the treatment of ferroptosis-associated diseases
L Liu, L Wang, Y Xiao, Y Liu, X Meng, X Shen - … Research-Modern Chinese …, 2024 - Elsevier
Backgrounds Ferroptosis, an iron-dependent cell death characterized by lethal lipid
peroxidation, has been involved in the pathogenesis of various diseases, such as …
peroxidation, has been involved in the pathogenesis of various diseases, such as …