Individual‐level brain morphological similarity networks: Current methodologies and applications

M Cai, J Ma, Z Wang, Y Zhao, Y Zhang… - CNS Neuroscience …, 2023 - Wiley Online Library
Aims The human brain is an extremely complex system in which neurons, clusters of
neurons, or regions are connected to form a complex network. With the development of …

Environmental neuroscience linking exposome to brain structure and function underlying cognition and behavior

F Liu, J Xu, L Guo, W Qin, M Liang, G Schumann… - Molecular …, 2023 - nature.com
Individual differences in human brain structure, function, and behavior can be attributed to
genetic variations, environmental exposures, and their interactions. Although genome-wide …

Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia

MA Di Biase, MP Geaghan, WR Reay, J Seidlitz… - Molecular …, 2022 - nature.com
Brain morphology differs markedly between individuals with schizophrenia, but the cellular
and genetic basis of this heterogeneity is poorly understood. Here, we sought to determine …

Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium

D Schijven, MC Postema… - Proceedings of the …, 2023 - National Acad Sciences
Left–right asymmetry is an important organizing feature of the healthy brain that may be
altered in schizophrenia, but most studies have used relatively small samples and …

Neuroimaging biomarkers define neurophysiological subtypes with distinct trajectories in schizophrenia

Y Jiang, J Wang, E Zhou, L Palaniyappan, C Luo… - Nature Mental …, 2023 - nature.com
Technical developments and improved access to neuroimaging techniques have brought us
closer to understanding the neuropathological origins of schizophrenia. Using data-driven …

Toward individualized connectomes of brain morphology

J Wang, Y He - Trends in Neurosciences, 2024 - cell.com
The morphological brain connectome (MBC) delineates the coordinated patterns of local
morphological features (such as cortical thickness) across brain regions. While classically …

Metabolic interactions between organs in overweight and obesity using total-body positron emission tomography

W Lu, Y Duan, K Li, Z Cheng, J Qiu - International Journal of Obesity, 2024 - nature.com
Abstract Background and Objectives Overweight and obesity is a complex condition
resulting from unbalanced energy homeostasis among various organs. However, systemic …

Identifying the individual metabolic abnormities from a systemic perspective using whole-body PET imaging

T Sun, Z Wang, Y Wu, F Gu, X Li, Y Bai, C Shen… - European Journal of …, 2022 - Springer
Introduction Distinct physiological states arise from complex interactions among the various
organs present in the human body. PET is a non-invasive modality with numerous …

Resolving heterogeneity in obsessive–compulsive disorder through individualized differential structural covariance network analysis

S Han, Y Xu, HR Guo, K Fang, Y Wei, L Liu… - Cerebral …, 2023 - academic.oup.com
Background The high heterogeneity of obsessive–compulsive disorder (OCD) denies
attempts of traditional case–control studies to derive neuroimaging biomarkers indicative of …

Identification of shared and distinct patterns of brain network abnormality across mental disorders through individualized structural covariance network analysis

S Han, K Xue, Y Chen, Y Xu, S Li, X Song… - Psychological …, 2023 - cambridge.org
BackgroundMental disorders, including depression, obsessive compulsive disorder (OCD),
and schizophrenia, share a common neuropathy of disturbed large-scale coordinated brain …