The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications

JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing global pandemic has presented a health emergency of unprecedented …

Pharmacological agents targeting thromboinflammation in COVID-19: review and implications for future research

B Bikdeli, MV Madhavan, A Gupta… - Thrombosis and …, 2020 - thieme-connect.com
Coronavirus disease 2019 (COVID-19), currently a worldwide pandemic, is a viral illness
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The …

Blood platelets and sepsis pathophysiology: a new therapeutic prospect in critical ill patients?

A Dewitte, S Lepreux, J Villeneuve, C Rigothier… - Annals of intensive …, 2017 - Springer
Beyond haemostasis, platelets have emerged as versatile effectors of the immune response.
The contribution of platelets in inflammation, tissue integrity and defence against infections …

[HTML][HTML] Meta-analysis of the effect of aspirin on mortality in COVID-19

HM Salah, JL Mehta - The American journal of cardiology, 2021 - ncbi.nlm.nih.gov
Elsevier hereby grants permission to make all its COVID-19-related research that is
available on the COVID-19 resource centre-including this research content-immediately …

Platelets and multi-organ failure in sepsis

E Greco, E Lupia, O Bosco, B Vizio… - International journal of …, 2017 - mdpi.com
Platelets have received increasing attention for their role in the pathophysiology of infectious
disease, inflammation, and immunity. In sepsis, a low platelet count is a well-known …

[HTML][HTML] Active prescription of low-dose aspirin during or prior to hospitalization and mortality in COVID-19: A systematic review and meta-analysis of adjusted effect …

JW Martha, R Pranata, MA Lim, A Wibowo… - International Journal of …, 2021 - Elsevier
Background This study aimed to investigate whether the active prescription of low-dose
aspirin during or prior to hospitalization affects mortality in patients with coronavirus disease …

Preventing the development of severe COVID-19 by modifying immunothrombosis

G Morris, CC Bortolasci, BK Puri, L Olive, W Marx… - Life sciences, 2021 - Elsevier
Background COVID-19-associated acute respiratory distress syndrome (ARDS) is
associated with significant morbidity and high levels of mortality. This paper describes the …

Use of aspirin in reduction of mortality of COVID‐19 patients: A meta‐analysis

R Srivastava, A Kumar - International journal of clinical practice, 2021 - Wiley Online Library
COVID‐19 infection, affecting every one of us from the last year. Emerging reports have
indicated thromboembolism in serious cases of COVID‐19. The aspirin is useful to reduce …

Does aspirin have an effect on risk of death in patients with COVID-19? A meta-analysis

S Ma, W Su, C Sun, S Lowe, Z Zhou, H Liu… - European Journal of …, 2022 - Springer
Purpose The coronavirus disease 2019 (COVID-19) pandemic has shown unprecedented
impact world-wide since the eruption in late 2019. Importantly, emerging reports suggest an …

Platelet Versus Megakaryocyte: Who Is the Real Bandleader of Thromboinflammation in Sepsis?

C Garcia, B Compagnon, M Poëtte, MP Gratacap… - Cells, 2022 - mdpi.com
Platelets are mainly known for their key role in hemostasis and thrombosis. However,
studies over the last two decades have shown their strong implication in mechanisms …