[PDF][PDF] Chromaffin cells of the adrenal medulla: physiology, pharmacology, and disease

E Carbone, R Borges, LE Eiden, AG García… - Compr …, 2019 - researchgate.net
Chromaffin cells (CCs) of the adrenal gland and the sympathetic nervous system produce
the catecholamines (epinephrine and norepinephrine; EPI and NE) needed to coordinate …

Natural product synthesis through the lens of informatics

S Woo, RA Shenvi - Accounts of chemical research, 2021 - ACS Publications
Conspectus Retrosynthetic analysis emerged in the 1960s as a teaching tool with profound
implications. Its educational value can be appreciated by a glance at total synthesis …

[HTML][HTML] Effects of ammonia toxicity on the histopathology, detoxification, oxidative stress, and immune response of the cuttlefish Sepia pharaonis and the mitigation of …

Y Liang, Y Wu, J Li, R Peng, M Jiang, X Jiang… - Ecotoxicology and …, 2022 - Elsevier
In this study, γ-aminobutyric acid (GABA) was examined as an additional supplement to
improve the ammonia stress resistance of S. pharaonis. Specifically, we added different …

[HTML][HTML] Oxytocin and vasopressin, and the GABA developmental shift during labor and birth: friends or foes?

Y Ben-Ari - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Oxytocin (OT) and vasopressin (AVP) are usually associated with sociability and reduced
stress for the former and antidiuretic agent associated with severe stress and pathological …

Molecular determinants of the adrenal gland functioning related to stress-sensitive hypertension in ISIAH rats

LA Fedoseeva, LO Klimov, NI Ershov… - BMC genomics, 2016 - Springer
Background The adrenals are known as an important link in pathogenesis of arterial
hypertensive disease. The study was directed to the adrenal transcriptome analysis in ISIAH …

Experimental pharmacological approaches to reverse impaired awareness of hypoglycemia—a review

HZ Hashmi, A Khowaja, A Moheet - Frontiers in Pharmacology, 2024 - frontiersin.org
The colossal global burden of diabetes management is compounded by the serious
complication of hypoglycemia. Protective physiologic hormonal and neurogenic …

[HTML][HTML] Basal and stress-induced network activity in the adrenal medulla in vivo

JR Lopez Ruiz, SA Ernst, RW Holz… - Frontiers in …, 2022 - frontiersin.org
The adrenal medulla plays a critical role in mammalian homeostasis and the stress
response. It is populated by clustered chromaffin cells that secrete epinephrine or …

GABA induces a hormonal counter-regulatory response in subjects with long-standing type 1 diabetes

D Espes, H Liljebäck, H Hill, A Elksnis… - BMJ Open Diabetes …, 2021 - drc.bmj.com
Introduction Experimentally, gamma-aminobutyric acid (GABA) has been found to exert
immune-modulatory effects and induce beta-cell regeneration, which make it a highly …

Effect of developmental NMDAR antagonism with CGP 39551 on aspartame-induced hypothalamic and adrenal gene expression

KS Collison, A Inglis, S Shibin, S Saleh, B Andres… - PLoS …, 2018 - journals.plos.org
Rationale Aspartame (L-aspartyl phenylalanine methyl ester) is a non-nutritive sweetener
(NNS) approved for use in more than 6000 dietary products and pharmaceuticals consumed …

Genome-wide screening for genetic variants in polyadenylation signal (PAS) sites in mouse selection lines for fatness and leanness

M Šimon, Š Mikec, NM Morton, SS Atanur, J Konc… - Mammalian …, 2023 - Springer
Alternative polyadenylation (APA) determines mRNA stability, localisation, translation and
protein function. Several diseases, including obesity, have been linked to APA. Studies have …