Boron containing compounds as protease inhibitors
R Smoum, A Rubinstein, VM Dembitsky… - Chemical …, 2012 - ACS Publications
Proteases form one of the largest and more important groups of enzymes. They selectively
catalyze the hydrolysis of peptide bonds and can be divided into four major classes …
catalyze the hydrolysis of peptide bonds and can be divided into four major classes …
Human Ovarian Tumors Express γ-Glutamyl Transpeptidase
MH Hanigan, HF Frierson Jr, JE Brown, MA Lovell… - Cancer Research, 1994 - AACR
Gamma-glutamyl transpeptidase (GGT) is a cell surface enzyme that initiates the cleavage of
extracellular glutathione, thereby providing the cell with the amino acids necessary for …
extracellular glutathione, thereby providing the cell with the amino acids necessary for …
Development and evaluation of a boronate inhibitor of γ-glutamyl transpeptidase
RE London, SA Gabel - Archives of Biochemistry and Biophysics, 2001 - Elsevier
γ-Glutamyl transpeptidase (γ-GT) plays a central role in the metabolism of glutathione and is
also a marker for neoplasia and cell transformation. We have investigated the compound l-2 …
also a marker for neoplasia and cell transformation. We have investigated the compound l-2 …
4-Hydroxynonenal increases γ-glutamyl transpeptidase gene expression through mitogen-activated protein kinase pathways
γ-Glutamyl transpeptidase (GGT) plays key roles in the metabolism of glutathione. Previous
studies have shown that GGT expression was increased by oxidants, but the mechanism …
studies have shown that GGT expression was increased by oxidants, but the mechanism …
Neoplastic transformation and lineage switching of rat liver epithelial cells by retrovirus‐associated oncogenes
S Garfield, BE Huber, P Nagy… - Molecular …, 1988 - Wiley Online Library
Tumors produced by a chemically transformed rat liver epithelial (RLE) cell line and its
single cell‐derived clonal subpopulations demonstrate wide‐ranging morphological …
single cell‐derived clonal subpopulations demonstrate wide‐ranging morphological …
Density‐dependent regulation of cell surface γ‐glutamyl transpeptidase in cultured glial cells
K Morgenstern, O Hanson‐Painton… - Journal of cellular …, 1992 - Wiley Online Library
A decline in cell surface γ‐glutamyl transpeptidase specific activity was previously observed
to be concomitant with C6 glial cell proliferation. To elucidate the underlying factor (s) …
to be concomitant with C6 glial cell proliferation. To elucidate the underlying factor (s) …
The expression of c-myc related to the proliferation and transformation of rat liver-derived epithelial cells
S Sinha, GE Neal, RF Legg, JV Watson… - British journal of …, 1989 - nature.com
The expression of c-myc protein was studied in primary cultures of rat hepatocytes and rat
liver-derived epithelial cell lines. The levels of the protein were determined by flow cytometry …
liver-derived epithelial cell lines. The levels of the protein were determined by flow cytometry …
Gamma-glutammiltransferasi (GGT): biochimica clinica e patologia umana (Rassegna)
M Franzini, A Corti, C Mammini - biochimica clinica, 2009 - iris.sssup.it
γ-glutamyltransferase: clinical biochemistry and human pathophysiology. Serum γ-
glutamyltransferase (GGT) activity is a sensitive test of liver function, but its clinical use is …
glutamyltransferase (GGT) activity is a sensitive test of liver function, but its clinical use is …