Much has been made about JLW Thudichum's colorful, and one could say clairvoyant,
naming of sphingosine “in commemoration of the many enigmas which it presented to the …

Glycomics is a broad and emerging scientific discipline focused on defining the structures
and functional roles of glycans in biological systems. The staggering complexity of the …

Edited by CT Rhodes, BPharm, PhD, FRIC, MPS and RE Hone, BPharm, MPS The editors of
this book are convinced that the development and use of automation in the field of …

Glycosphingolipids (GSL s) comprise a heterogeneous group of membrane lipids formed by
a ceramide backbone covalently linked to a glycan moiety. Hundreds of different glycans …

" Sphingosin" was first described by JLW Thudichum in 1884 and structurally characterized
as 2S, 3R, 4E-2-aminooctadec-4-ene-1, 3-diol in 1947 by Herb Carter, who also proposed …

Sphingolipids are a highly diverse category of bioactive compounds. This article describes
methods that have been validated for the extraction, liquid chromatographic (LC) separation …

Electrospray and matrix assisted laser desorption ionization generate abundant molecular
ion species from all known lipids that have long chain fatty acyl groups esterified or …

Gangliosides are sialic acid‐containing glycosphingolipids. They occur especially on the
cellular surfaces of neuronal cells, where they form a complex pattern, but are also found in …

Mass spectrometry plays an increasingly important role in structural glycomics. This review
provides an overview on currently used mass spectrometric approaches such as the …

The main cellular receptors of Shiga toxins (Stxs), the neutral glycosphingolipids (GSLs),
globotriaosylceramide (Gb3Cer/CD77) and globotetraosylceramide (Gb4Cer), are …