Regulating the regulators: the future prospects for transcription-factor-based agricultural biotechnology products
It is now more than a decade since the first commercially successful genetically engineered
agricultural crops were launched (Castle et al., 2006). These first products were based in …
agricultural crops were launched (Castle et al., 2006). These first products were based in …
Comparative analysis of gene regulatory networks: from network reconstruction to evolution
D Thompson, A Regev, S Roy - Annual review of cell and …, 2015 - annualreviews.org
Regulation of gene expression is central to many biological processes. Although
reconstruction of regulatory circuits from genomic data alone is therefore desirable, this …
reconstruction of regulatory circuits from genomic data alone is therefore desirable, this …
YEASTRACT+: a portal for cross-species comparative genomics of transcription regulation in yeasts
The YEASTRACT+ information system (http://YEASTRACT-PLUS. org/) is a wide-scope tool
for the analysis and prediction of transcription regulatory associations at the gene and …
for the analysis and prediction of transcription regulatory associations at the gene and …
The frailty of adaptive hypotheses for the origins of organismal complexity
M Lynch - Proceedings of the National Academy of …, 2007 - National Acad Sciences
The vast majority of biologists engaged in evolutionary studies interpret virtually every
aspect of biodiversity in adaptive terms. This narrow view of evolution has become …
aspect of biodiversity in adaptive terms. This narrow view of evolution has become …
[HTML][HTML] A Phenotypic Profile of the Candida albicans Regulatory Network
OR Homann, J Dea, SM Noble, AD Johnson - PLoS genetics, 2009 - journals.plos.org
Candida albicans is a normal resident of the gastrointestinal tract and also the most
prevalent fungal pathogen of humans. It last shared a common ancestor with the model …
prevalent fungal pathogen of humans. It last shared a common ancestor with the model …
The Awesome Power of Yeast Evolutionary Genetics: New Genome Sequences and Strain Resources for the Saccharomyces sensu stricto Genus
High-quality, well-annotated genome sequences and standardized laboratory strains fuel
experimental and evolutionary research. We present improved genome sequences of three …
experimental and evolutionary research. We present improved genome sequences of three …
High-resolution DNA-binding specificity analysis of yeast transcription factors
Transcription factors (TFs) regulate the expression of genes through sequence-specific
interactions with DNA-binding sites. However, despite recent progress in identifying in vivo …
interactions with DNA-binding sites. However, despite recent progress in identifying in vivo …
[HTML][HTML] Horizontal transfer of a large and highly toxic secondary metabolic gene cluster between fungi
Genes involved in intermediary and secondary metabolism in fungi are frequently physically
linked or clustered. For example, in Aspergillus nidulans the entire pathway for the …
linked or clustered. For example, in Aspergillus nidulans the entire pathway for the …
[HTML][HTML] Transcriptional Regulation of Carbohydrate Metabolism in the Human Pathogen Candida albicans
C Askew, A Sellam, E Epp, H Hogues, A Mullick… - PLoS …, 2009 - journals.plos.org
Glycolysis is a metabolic pathway that is central to the assimilation of carbon for either
respiration or fermentation and therefore is critical for the growth of all organisms …
respiration or fermentation and therefore is critical for the growth of all organisms …
DNA-binding specificity changes in the evolution of forkhead transcription factors
S Nakagawa, SS Gisselbrecht… - Proceedings of the …, 2013 - National Acad Sciences
The evolution of transcriptional regulatory networks entails the expansion and diversification
of transcription factor (TF) families. The forkhead family of TFs, defined by a highly …
of transcription factor (TF) families. The forkhead family of TFs, defined by a highly …