Inflammation is indispensable for host homeostasis against invading pathogens and efficient
wound healing upon tissue malfunction and has to be tightly controlled by various …

The formation of adipocytes from precursor stem cells involves a complex and highly
orchestrated programme of gene expression. Our understanding of the basic network of …

Adipose tissue (AT) plays a pivotal role in whole-body lipid and glucose homeostasis. AT
exerts metabolic control through various immunological mechanisms that instigated a new …

Osteoarthritis (OA), the leading cause of pain and disability worldwide, disproportionally
affects individuals with obesity. The mechanisms by which obesity leads to the onset and …

Insulin signalling is uniquely required for storing energy as fat in humans. While de novo
synthesis of fatty acids and triacylglycerol occurs mostly in liver, adipose tissue is the primary …

Abstract Background Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor,
has been extensively demonstrated to be associated with metabolic disorders, including …

Emerging evidence highlights that dysfunction of adipose tissue contributes to impaired
insulin sensitivity and systemic metabolic deterioration in obese state. Of note, adipocyte …

The peritoneal cavity is a fluid filled space that holds most of the abdominal organs,
including the omentum, a visceral adipose tissue that contains milky spots or clusters of …

Inflammation plays a central pathogenic role in the pernicious metabolic and end‐organ
sequelae of obesity. Among these sequelae, nonalcoholic fatty liver disease (NAFLD) has …

Although white AT can contribute to anti-infectious immune responses, it can also be
targeted and perturbed by pathogens. The AT's immune involvement is primarily due to …