In the last decades three-dimensional (3D) in vitro cancer models have been proposed as a
bridge between bidimensional (2D) cell cultures and in vivo animal models, the gold …

Pancreatic stellate cells (PSCs) and cancer-associated fibroblasts (CAFs) are highly
abundant cells in the pancreatic tumor microenvironment (TME) that modulate desmoplasia …

Cancer kills millions of individuals every year all over the world (Global Cancer
Observatory). The physiological and biomechanical processes underlying the tumor are still …

4-Phenyl-3-[2-(phenylamino) ethyl]-1 H-1, 2, 4-triazole-5 (4 H)-thione was used as a starting
compound for the synthesis of the corresponding 1, 2, 4-triazol-3-ylthioacetohydrazide …

Cancer is characterized by the uncontrolled division of cells, resulting in the formation of
tumors. The tumor microenvironment (TME) consists of a variety of cell types present within a …

Nanotechnological platforms offer advantages over conventional therapeutic and diagnostic
modalities. However, the efficient biointerfacing of nanomaterials for biomedical applications …

Minimal therapeutic advances have been achieved over the past two decades for
glioblastoma (GBM), which remains an unmet clinical need. Here, hypothesis‐driven stimuli …

Biomaterials embody a groundbreaking paradigm shift in the field of drug delivery and
human applications. Their versatility and adaptability have not only enriched therapeutic …

Traditional Chinese medicine (TCM) is the key to unlock treasures of Chinese civilization.
TCM and its compound play a beneficial role in medical activities to cure diseases …

Hyperthermic nanomedicines are particularly relevant for tackling human cancer, providing
a valuable alternative to conventional therapeutics. The early-stage preclinical performance …