[HTML][HTML] The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

E Mogilyansky, I Rigoutsos - Cell Death & Differentiation, 2013 - nature.com
Abstract The miR-17/92 cluster is among the best-studied microRNA clusters. Interest in the
cluster and its members has been increasing steadily and the number of publications has …

[HTML][HTML] Functions of lncRNA HOTAIR in lung cancer

G Loewen, J Jayawickramarajah, Y Zhuo… - Journal of hematology & …, 2014 - Springer
Long non-coding RNAs (lncRNAs) govern fundamental biochemical and cellular processes.
lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through …

MicroRNAs in human cancer

TA Farazi, JI Hoell, P Morozov, T Tuschl - MicroRNA cancer regulation …, 2013 - Springer
Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20–23-nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

Lung cancer cells and their sensitivity/resistance to cisplatin chemotherapy: Role of microRNAs and upstream mediators

M Ashrafizadeh, A Zarrabi, K Hushmandi, F Hashemi… - Cellular signalling, 2021 - Elsevier
Cisplatin (CP) is a well-known chemotherapeutic agent with excellent clinical effects. The
anti-tumor activity of CP has been demonstrated in different cancers such as breast, cervical …

[HTML][HTML] MicroRNAs and cancer: Key paradigms in molecular therapy

W Tan, B Liu, S Qu, G Liang, W Luo… - Oncology …, 2018 - spandidos-publications.com
MicroRNAs (miRNAs) are a type of small non-coding RNA molecule that performs an
important role in post‑transcriptional gene regulation. Since miRNAs were first identified in …

miRNAs in human cancer

TA Farazi, JI Spitzer, P Morozov… - The Journal of …, 2011 - Wiley Online Library
Mature microRNAs (miRNAs) are single‐stranded RNA molecules of 20–23 nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer

M Boeri, C Verri, D Conte, L Roz… - Proceedings of the …, 2011 - National Acad Sciences
The efficacy of computed tomography (CT) screening for early lung cancer detection in
heavy smokers is currently being tested by a number of randomized trials. Critical issues …

[HTML][HTML] MicroRNA in lung cancer: novel biomarkers and potential tools for treatment

K Inamura, Y Ishikawa - Journal of clinical medicine, 2016 - mdpi.com
Lung cancer is the leading cause of cancer death in men and women worldwide. The lack of
specific and sensitive tools for early diagnosis as well as still-inadequate targeted therapies …

Molecular biology of lung cancer: clinical implications

JE Larsen, JD Minna - Clinics in chest medicine, 2011 - chestmed.theclinics.com
Lung cancer is the leading cause of cancer-related death in men and women in the United
States, accounting for approximately 28% of total cancer deaths in 2010 despite comprising …

The Antidiabetic Drug Metformin Inhibits Gastric Cancer Cell Proliferation In Vitro and In Vivo

K Kato, J Gong, H Iwama, A Kitanaka, J Tani… - Molecular cancer …, 2012 - AACR
Recent studies suggest that metformin, which is commonly used as an oral anti-
hyperglycemic agent of the biguanide family, may reduce cancer risk and improve …