Purpose Tall stature is defined as height greater than the threshold of more than 2 standard
deviations above the average population height for age, sex, and ethnicity. Many studies …

Precocious puberty has been classically defined as the onset of sexual secondary
characteristics in girls younger than 8 years and in boys younger than 9 years. The …

The pollution of endocrine disruptors and its impact on human reproductive system have
attracted much attention. Di-(2-ethylhexyl) phthalate (DEHP), an environmental endocrine …

Objective: The optimal treatment for girls with central precocious puberty (CPP) is unknown.
We conducted a network meta-analysis to evaluate the efficacy and safety of existing …

Background To date, the gonadotropin-releasing hormone (GnRH) stimulation test is still the
gold standard for precocious puberty (PP) diagnosis. However, it has many disadvantages …

O início da puberdade caracteriza-se pelo aumento de amplitude e frequência dos pulsos
do hormônio secretor de gonadotrofinas (GnRH) após um período de relativa supressão …

Puberty is a complex biological process of sexual development, influenced by genetic,
metabolic-nutritional, environmental and socioeconomic factors, characterized by the …

Цель исследования: определить роль кисспептина в регуляции функции
репродуктивной системы. Материалы: литературные данные зарубежных авторов за …

The timing of puberty onset varies greatly among individuals, and much of this variation is
modulated by genetic factors. This study aimed to identify the kisspeptin receptor (KISS1R) …

The gut microbiota has been implicated in the context of sexual maturation during puberty,
with discernible differences in its composition before and after this critical developmental …