Mendelian randomization as a tool to gain insights into the mosaic causes of autoimmune diseases

C Chen, P Wang, RD Zhang, Y Fang, LQ Jiang… - Autoimmunity …, 2022 - Elsevier
Autoimmune diseases (ADs) are a broad range of disorders which are characterized by long-
term inflammation and tissue damage arising from an immune response against one's own …

[HTML][HTML] High folate, perturbed one-carbon metabolism and gestational diabetes mellitus

JM Williamson, AL Arthurs, MD Smith, CT Roberts… - Nutrients, 2022 - mdpi.com
Folate is a dietary micronutrient essential to one-carbon metabolism. The World Health
Organisation recommends folic acid (FA) supplementation pre-conception and in early …

[HTML][HTML] Homocysteine, cognitive functions, and degenerative dementias: state of the art

S Luzzi, V Cherubini, L Falsetti, G Viticchi, M Silvestrini… - Biomedicines, 2022 - mdpi.com
There is strong evidence that homocysteine is a risk factor not only for cerebrovascular
diseases but also for degenerative dementias. A recent consensus statement renewed the …

[HTML][HTML] Targeting metabolism in aortic aneurysm and dissection: from basic research to clinical applications

Q Wang, G Yesitayi, B Liu, D Siti… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Aortic aneurysm and dissection (AAD) are a group of insidious and lethal cardiovascular
diseases that characterized by seriously threatening the life and health of people, but lack …

[HTML][HTML] The Role of Fibrinogen, Homocysteine and Metabolic Syndrome's Alterations in Sudden Sensorineural Hearing Loss (SSHL): A Narrative Review

D Monzani, C Liberale, E Segato, F De Cecco, V Arietti… - Medicina, 2023 - mdpi.com
Fibrinogen and homocysteine (HCY) are molecules known to play a role in vascular
homeostasis, and their blood levels are often elevated in patients with metabolic syndrome …

Homocysteine levels in first-episode patients with psychiatric disorders

N Fan, W Zhao, Y Yun, L Bai, H An, Q Zhang… - Frontiers in …, 2024 - frontiersin.org
A high homocysteine (Hcy) level is a risk factor for schizophrenia, depression, and bipolar
disorder. However, the role of hyperhomocysteinemia as either an independent factor or an …

[PDF][PDF] miR-488-3p 靶向调控RAP1A 在同型半胱氨酸介导肝细胞自噬的作用研究

高源, 揭育祯, 马天龙, 汪乐新, 杨慧霞… - 中国比较医学 …, 2022 - zgbjyx.cnjournals.com
目的探讨微小RNA (miR-488-3p) 通过靶向调控RAS 癌基因家族成员RAP1A
在同型半胱氨酸介导肝细胞自噬中的作用. 方法体外常规培养人正常肝细胞(HL-7702) …

Do we need more guidance on thrombophilia testing? Challenges and special considerations

F Marongiu, MF Ruberto, S Marongiu… - Expert Review of …, 2024 - Taylor & Francis
Introduction Thrombophilia testing (TT) is a laboratory procedure designed to detect the risk
factors involved in the pathogenesis of vascular occlusions. The role of TT is also …

The correlations between serum Hcy level and seizures and cognitive function in patients after stroke

C Lan, Z Huang, X Luo… - American Journal of …, 2022 - journals.sagepub.com
Backgrounds Post-stroke cognitive dysfunction (PSCI), a set of illnesses ranging from
moderate cognitive impairment to dementia, which is one of the most prevalent …

[HTML][HTML] Adverse cardiac events of hypercholesterolemia are enhanced by sitagliptin in sprague dawley rats

HA Palfrey, A Kumar, R Pathak, KP Stone… - Nutrition & …, 2024 - Springer
Background Cardiovascular disease (CVD) affects millions worldwide and is the leading
cause of death among non-communicable diseases. Western diets typically comprise of …