Experimental Considerations for the Evaluation of Viral Biomolecular Condensates
CA Roden, AS Gladfelter - Annual Review of Virology, 2024 - annualreviews.org
Biomolecular condensates are nonmembrane-bound assemblies of biological polymers
such as protein and nucleic acids. An increasingly accepted paradigm across the viral tree …
such as protein and nucleic acids. An increasingly accepted paradigm across the viral tree …
[HTML][HTML] HIV persistence, latency, and cure approaches: where are we now?
TC Chou, NS Maggirwar, MD Marsden - Viruses, 2024 - mdpi.com
The latent reservoir remains a major roadblock to curing human immunodeficiency virus
(HIV) infection. Currently available antiretroviral therapy (ART) can suppress active HIV …
(HIV) infection. Currently available antiretroviral therapy (ART) can suppress active HIV …
Epitranscriptomic m6A modifications during reactivation of HIV-1 latency in CD4+ T cells
Despite effective antiretroviral therapy reducing HIV-1 viral loads to undetectable levels, the
presence of latently infected CD4+ T cells poses a major barrier to HIV-1 cure. N 6 …
presence of latently infected CD4+ T cells poses a major barrier to HIV-1 cure. N 6 …
Sustained antiviral response against in vitro HIV-1 infection in peripheral blood mononuclear cells from people with chronic myeloid leukemia treated with ponatinib
M Manzanares, F Ramos-Martín… - Frontiers in …, 2024 - frontiersin.org
HIV-1 infection cannot be cured due to long-lived viral reservoirs formed by latently infected
CD4+ T cells.“Shock and Kill” strategy has been considered to eliminate the viral reservoir …
CD4+ T cells.“Shock and Kill” strategy has been considered to eliminate the viral reservoir …
Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal
CN Gray, M Ashokkumar, DH Janssens, J Kirchherr… - bioRxiv, 2024 - biorxiv.org
The latent HIV reservoir is a major barrier to HIV cure. Combining latency reversal agents
(LRAs) with differing mechanisms of action such as AZD5582, a non-canonical NF-kB …
(LRAs) with differing mechanisms of action such as AZD5582, a non-canonical NF-kB …
704 Zoledronic acid: challenges and pitfalls amid rehabilitation in primary osteoporosis and beyond
AF Florescu, OC Sima, M Costăchescu… - Balneo and PRM …, 2024 - bioclima.ro
Zoledronate (or zoledronic acid) represents a standard (guideline-based) approach in the
area of anti-resorptive medication (namely, an annual 15-minute perfusion of 5 mg for os …
area of anti-resorptive medication (namely, an annual 15-minute perfusion of 5 mg for os …