An efficient approach to access 2,5‐disubstituted 1,3,4‐oxadiazoles by oxidation of 2‐arenoxybenzaldehyde N‐acyl hydrazones with molecular iodine

H Başpınar Küçük, A Alhonaish, T Yıldız… - …, 2022 - Wiley Online Library
An oxidative cyclization of 2‐arenoxybenzaldehyde N‐acyl hydrazones 3 a–o was
employed to synthesize new 2, 5‐disubstituted 1, 3, 4‐oxadiazole compounds 4 a–d, 4 f–i, 4 …

Intramolecular Friedel–Crafts Reaction with Trifluoroacetic Acid: Synthesizing Some New Functionalized 9-Aryl/Alkyl Thioxanthenes

H Deniz, T Yıldız, H Başpınar Küçük - ACS omega, 2024 - ACS Publications
In this study, a series of halogen-substituted thioxanthenes were synthesized because the
most important and biologically active derivatives of xanthenes are thioxanthenes. In order …

New Strategy for the Synthesis of Some Valuable Chiral 1, 3-Diols with High Enantiomeric Purity: New Organocatalyst, Asymmetric Aldol Reaction, and Reduction

T Yıldız, B Hasdemir, H Yaşa… - ACS …, 2024 - ACS Publications
Chiral 1, 3-diols are highly valuable molecules used in industries such as pharmaceuticals,
cosmetics, and agriculture. Therefore, in this study, a new strategy was developed to …

Stearyl palmitate a multi-target inhibitor against breast cancer: in-silico, in-vitro & in-vivo approach

L Ravi, A Kumar K, S Kumari GR… - Journal of …, 2023 - Taylor & Francis
Multi-target inhibitors are currently trending in the pharmaceutical research, as they possess
increased efficacy and reduced toxicity. In this study multi-target inhibitors for breast cancer …

Synthesis of (E)-7-arylidene-5-(hydroxy (aryl) methyl) bicyclo [3.2. 0] heptan-6-one derivatives as anti-cancer agents

M Ceylan, B Zorlu, AŞ Yağlıoğlu… - Journal of New …, 2023 - dergipark.org.tr
7, 7-Dichlorobicyclo [3.2. 0] heptan-6-one was prepared by adding dichloroketene to
cyclopentene. Reduction of 7, 7-dichlorobicyclo [3.2. 0] heptan-6-one with Zn in acetic acid …