While NLRP3 contributes to kidney fibrosis, the function of most NOD‐like receptors (NLRs)
in chronic kidney disease (CKD) remains unexplored. To identify further NLR members …

We tested the hypothesis that loss of Nlrp3 would protect mice from Western diet-induced
adipose tissue (AT) inflammation and associated glucose intolerance and cardiovascular …

The mechanisms triggering renal inflammation in chronic kidney disease (CKD) are unclear.
We performed a detailed analysis of the time course of innate and adaptive immunity …

BACKGROUND Renal fibrosis occurs largely through epithelial–mesenchymal transition
(EMT). This study explored the beneficial effects of a human umbilical cord mesenchymal …

Vascular calcification (VC) is common in chronic kidney disease (CKD), where
cardiovascular mortality remains the leading cause of death. Here, we examined the role of …

Protein overload of proximal tubular cells (PTCs) can promote interstitial injury by unclear
mechanisms that may involve activation of innate immunity. We investigated whether …

Abstract Context Yiqi Huoxue Tongluo recipe (YHTR) is a traditional Chinese medicine for
the treatment of chronic kidney disease, but its exact mechanism is not clear. Objectives To …

Spinal cord injury (SCI) is one kind of severe traumatic injury, resulting in systemic
inflammatory response syndrome and secondary lung injury, which is an important …

Inflammasome activation: unraveling the link between chronic kidney disease and atrial
fibrillation Inflammasome activation: unraveling the link between chronic kidney disease and …

Arteriovenous fistulas (AVFs) have long been used as dialysis access in patients with end-
stage renal disease; however, their maturation and long-term patency still fall short of clinical …