Insights on persistent airway infection by non-typeable Haemophilus influenzae in chronic obstructive pulmonary disease

CP Ahearn, MC Gallo, TF Murphy - Pathogens and disease, 2017 - academic.oup.com
Abstract Non-typeable Haemophilus influenzae (NTHi) is the most common bacterial cause
of infection of the lower airways in adults with chronic obstructive pulmonary disease …

Otitis media: recent advances in otitis media vaccine development and model systems

A Zahid, JC Wilson, ID Grice, IR Peak - Frontiers in Microbiology, 2024 - frontiersin.org
Otitis media is an inflammatory disorder of the middle ear caused by airways-associated
bacterial or viral infections. It is one of the most common childhood infections as globally …

Insights into the population structure and pan-genome of Haemophilus influenzae

M Pinto, A González-Díaz, MP Machado… - Infection, Genetics and …, 2019 - Elsevier
The human-restricted bacterium Haemophilus influenzae is responsible for respiratory
infections in both children and adults. While colonization begins in the upper airways, it can …

An invasive Haemophilus influenzae serotype b infection in an Anglo-Saxon plague victim

M Guellil, M Keller, JM Dittmar, SA Inskip, C Cessford… - Genome biology, 2022 - Springer
Abstract Background The human pathogen Haemophilus influenzae was the main cause of
bacterial meningitis in children and a major cause of worldwide infant mortality before the …

Bronchiectasis in children: current concepts in immunology and microbiology

SJ Pizzutto, KM Hare, JW Upham - Frontiers in pediatrics, 2017 - frontiersin.org
Bronchiectasis is a complex chronic respiratory condition traditionally characterized by
chronic infection, airway inflammation, and progressive decline in lung function. Early …

Antagonistic pleiotropy in the bifunctional surface protein FadL (OmpP1) during adaptation of Haemophilus influenzae to chronic lung infection associated with chronic …

J Moleres, A Fernández-Calvet, RL Ehrlich, S Martí… - MBio, 2018 - Am Soc Microbiol
Tracking bacterial evolution during chronic infection provides insights into how host
selection pressures shape bacterial genomes. The human-restricted opportunistic pathogen …

It Takes Two to Tango: Combining Conventional Culture With Molecular Diagnostics Enhances Accuracy of Streptococcus pneumoniae Detection and Pneumococcal …

WR Miellet, J van Veldhuizen, D Litt… - Frontiers in …, 2022 - frontiersin.org
Background The specificity of molecular methods for the detection of Streptococcus
pneumoniae carriage is under debate. We propose a procedure for carriage surveillance …

Predominant bacterial and viral otopathogens identified within the respiratory tract and middle ear of urban Australian children experiencing otitis media are diversely …

CC Ngo, HM Massa, BA McMonagle… - Frontiers in Cellular …, 2022 - frontiersin.org
Background Otitis media (OM) is one of the most common infections in young children,
arising from bacterial and/or viral infection of the middle ear. Globally, Streptococcus …

Simultaneous Identification of Haemophilus Influenzae and Haemophilus Haemolyticus using Real-Time PCR

EP Price, TM Harris, J Spargo, E Nosworthy… - Future …, 2017 - Taylor & Francis
Aim: To design a highly specific and sensitive multiplex real-time PCR assay for the
differentiation of the pathogen Haemophilus influenzae from its nonpathogenic near …

Genomic classification and antimicrobial resistance profiling of Streptococcus pneumoniae and Haemophilus influenzae isolates associated with paediatric otitis …

B Lobb, MC Lee, CL McElheny, Y Doi, K Yahner… - BMC Infectious …, 2023 - Springer
Acute otitis media (AOM) is the most common childhood bacterial infectious disease
requiring antimicrobial therapy. Most cases of AOM are caused by translocation of …