Self-assembly drug-albumin nanocomposites for nonalcoholic fatty liver disease treatment

W Jing, M Jiang, X Fu, J Yang, L Chen, F Leng… - International Journal of …, 2022 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a chronic metabolic liver disease closely related
to obesity, which has become a global health problem. However, current pharmacological …

Hypoxia causes sex-specific hepatic toxicity at the transcriptome level in marine medaka (Oryzias melastigma)

KP Lai, N Tam, SY Wang, X Lin, TF Chan, DWT Au… - Aquatic Toxicology, 2020 - Elsevier
Hypoxia, a low environmental oxygen level, is a common problem in the ocean globally.
Hypoxia has been known to cause disruption to the endocrine system of marine organisms …

[HTML][HTML] Allomyrina dichotoma Larva Extract Ameliorates the Hepatic Insulin Resistance of High-Fat Diet-Induced Diabetic Mice

K Kim, GD Bae, M Lee, EY Park, DJ Baek, CY Kim… - Nutrients, 2019 - mdpi.com
Allomyrina dichotoma larva is a nutritional-worthy future food resource and it contributes to
multiple pharmacological functions. However, its antidiabetic effect and molecular …

Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors

M Saydmohammed, A Jha, V Mahajan… - Experimental …, 2021 - journals.sagepub.com
Metabolic syndrome is a complex disease that involves multiple organ systems including a
critical role for the liver. Non-alcoholic fatty liver disease (NAFLD) is a key component of the …

Protective Effect of a Mixture of Astragalus membranaceus and Lithospermum erythrorhizon Extract against Hepatic Steatosis in High Fat Diet‐Induced Nonalcoholic …

DJ Choi, SC Kim, GE Park, BR Choi… - Evidence‐Based …, 2020 - Wiley Online Library
The present study aimed to evaluate the potential synergistic and protective effects of
ALM16, a mixture of Astragalus membranaceus (AM) and Lithospermum erythrorhizon (LE) …

[HTML][HTML] Protective role of resveratrol against VCM-induced hepatotoxicity in male Wistar rats

FS Alshehri, NM Alorfi - Frontiers in Pharmacology, 2023 - frontiersin.org
Background: Vancomycin is a glycopeptide antibiotic with a high risk of acute liver injury.
Resveratrol is believed to protect the liver against toxicity. Aim: To investigate the ability of …

[HTML][HTML] Machine learning technology for evaluation of liver fibrosis, inflammation activity and steatosis (LIVERFAStTM)

A Aravind, AG Bahirvani, R Quiambao… - Journal of Intelligent …, 2020 - scirp.org
Using the latest available artificial intelligence (AI) technology, an advanced algorithm
LIVERFAStTM has been used to evaluate the diagnostic accuracy of machine learning (ML) …

[HTML][HTML] Circulatory bone morphogenetic protein (BMP) 8B is a non-invasive predictive biomarker for the diagnosis of non-alcoholic steatohepatitis (NASH)

N Mounika, A Yadav, P Kamboj, SK Banerjee, UJ Deka… - Plos one, 2023 - journals.plos.org
Background Nonalcoholic fatty liver disease (NAFLD) is a complex disease which is
characterized by the deposition of fats in the hepatocytes. Further, it progresses to …

[HTML][HTML] Energy restriction in obese women suggest linear reduction of hepatic fat content and time-dependent metabolic improvements

HE Johansson, D Edholm, J Kullberg, F Rosqvist… - Nutrition & …, 2019 - nature.com
Energy restriction reduces liver fat, improves hepatic insulin resistance and lipid metabolism.
However, temporal data in which these metabolic improvements occur and their interplay is …

[HTML][HTML] Standardized Hydrangea serrata (Thunb.) Ser. Extract Ameliorates Obesity in db/db Mice

HS Han, KS Chung, YK Shin, SH Lee, KT Lee - Nutrients, 2021 - mdpi.com
We previously reported the potential anti-obesity effects of the water extract of Hydrangea
serrata (Thunb.) Ser. leaves (WHS) in high-fat diet-induced obese mice. As an extension of …