Peripheral artery disease affects around 13% of the Western population who are more than
50 years old. 1 It is most commonly due to atherosclerosis, where an atherosclerotic plaque …

Peripheral artery disease (PAD) of the lower extremities is a common manifestation of
atherosclerosis that is increasing in global prevalence and in the associated public health …

Background Patients with peripheral artery disease have an increased risk of cardiovascular
morbidity and mortality. Antiplatelet agents are widely used to reduce these complications …

Background: Patients with lower extremity peripheral artery disease (PAD) are at increased
risk of major adverse cardiovascular events (MACE) and major adverse limb events (MALE) …

Importance Patients with symptomatic lower extremity peripheral artery disease (LE-PAD)
experience an increased risk of major vascular events. There is limited information on what …

Background: The VOYAGER PAD trial (Vascular Outcomes Study of ASA Along With
Rivaroxaban in Endovascular or Surgical Limb Revascularization for Peripheral Artery …

Post-transcriptional modifications play pivotal roles in various pathological processes and
ischemic disorders. However, the role of N7-methylguanosine (m7G), particularly m7G in …

Background Patients with peripheral artery disease (PAD) undergoing a lower-extremity
revascularization are at heightened risk for ischemic cardiac and limb events. Although …

Background Long-term cardiovascular and limb outcomes after revascularization for
peripheral artery disease and, in particular, prognosis after post-procedure major adverse …

Thrombo-inflammation describes the complex interplay between blood coagulation and
inflammation that plays a critical role in cardiovascular diseases. The third Maastricht …