The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury

CS Ahuja, A Mothe, M Khazaei… - Stem cells …, 2020 - academic.oup.com
Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …

Schwann cell transplantation for spinal cord injury repair: its significant therapeutic potential and prospectus

H Kanno, DD Pearse, H Ozawa, E Itoi… - Reviews in the …, 2015 - degruyter.com
Abstract Transplantation of Schwann cells (SCs) is a promising therapeutic strategy for
spinal cord repair. The introduction of SCs into the injured spinal cord has been shown to …

Human mesenchymal stem cells modulate inflammatory cytokines after spinal cord injury in rat

L Machová Urdzíková, J Růžička, M LaBagnara… - International journal of …, 2014 - mdpi.com
Transplantation of mesenchymal stem cells (MSC) improves functional recovery in
experimental models of spinal cord injury (SCI); however, the mechanisms underlying this …

[HTML][HTML] Effect of mesenchymal stem cells and melatonin on experimentally induced peripheral nerve injury in rats

SA Khodir, S Imbaby, MSAA Amer, MM Atwa… - Biomedicine & …, 2024 - Elsevier
Injury of a peripheral nerve (PNI) leads to both ischemic and inflammatory alterations. Sciatic
nerve injury (SNI) represents the most widely used model for PNI. Mesenchymal stem cell …

The comparative effects of schwann cells and wharton's jelly mesenchymal stem cells on the aim2 inflammasome activity in an experimental model of spinal cord …

E Kharazinejad, G Hassanzadeh, A Sahebkar… - Neuroscience, 2023 - Elsevier
Inflammasome activation and the consequent release of pro-inflammatory cytokines play a
crucial role in the development of sensory/motor deficits following spinal cord injury (SCI) …

Repairing and analgesic effects of umbilical cord mesenchymal stem cell transplantation in mice with spinal cord injury

L Wu, X Pan, H Chen, X Fu, J Jiang… - BioMed Research …, 2020 - Wiley Online Library
Transplantation of human umbilical cord mesenchymal stem cells (hUC‐MSCs) into spinal
cord injury (SCI) may alleviate neuropathic pain and promote functional recovery. The …

Invited review: Utilizing peripheral nerve regenerative elements to repair damage in the CNS

N El Seblani, AS Welleford, JE Quintero… - Journal of Neuroscience …, 2020 - Elsevier
An ongoing question in neuroscience is how the peripheral nervous system can repair itself
following an injury or insult whereas the central nervous system has a profoundly limited …

Combined effects of rat Schwann cells and 17β-estradiol in a spinal cord injury model

Z Namjoo, F Moradi, R Aryanpour, A Piryaei… - Metabolic brain …, 2018 - Springer
Spinal cord injury (SCI) is a devastating traumatic event which burdens the affected
individuals and the health system. Schwann cell (SC) transplantation is a promising repair …

Improved neural regeneration with olfactory ensheathing cell inoculated PLGA scaffolds in spinal cord injury adult rats

C Wang, C Sun, Z Hu, X Huo, Y Yang, X Liu… - Neurosignals, 2018 - karger.com
Abstract Background/Aims: Every year, around the world, between 250000 and 500000
people suffer from spinal cord injury (SCI). This study investigated the potential for poly …

The efficacy of Schwann cell transplantation on motor function recovery after spinal cord injuries in animal models: a systematic review and meta-analysis

M Hosseini, M Yousefifard, M Baikpour… - Journal of chemical …, 2016 - Elsevier
Aim This article aimed to assess the efficacy of Schwann cell transplantation on motor
function recovery in animal model of spinal cord injuries via meta-analysis. Methods An …