Traditional risk factors for obesity and the metabolic syndrome, such as excess energy
intake and lack of physical activity, cannot fully explain the high prevalence of these …

To accommodate daily recurring environmental changes, animals show cyclic variations in
behaviour and physiology, which include prominent behavioural states such as sleep–wake …

Visible light synchronizes the human biological clock in the suprachiasmatic nuclei of the
hypothalamus to the solar 24‐hour cycle. Short wavelengths, perceived as blue color, are …

Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …

Despite much attention on digital media use and young peoples' sleep, the literature on
digital media and its impact on sleep in older adolescents and young adults remains to be …

Architectural lighting has potent biological effects but applied lighting practices that
capitalize on this potential have been limited. In this review, we endeavor to consolidate and …

The importance of circadian biology has rarely been considered in pre-clinical studies, and
even more when translating to the bedside. Circadian biology is becoming a critical factor for …

Artificial light at night (ALAN) is increasing exponentially worldwide, accelerated by the
transition to new efficient lighting technologies. However, ALAN and resulting light pollution …

Most teenagers are chronically sleep deprived. One strategy proposed to lengthen
adolescent sleep is to delay secondary school start times. This would allow students to wake …

The past twenty years have witnessed the most remarkable breakthroughs in our
understanding of the molecular and cellular mechanisms that underpin circadian …