Use of rodents as models of human diseases

TF Vandamme - Journal of Pharmacy and Bioallied Sciences, 2014 - journals.lww.com
Advances in molecular biology have significantly increased the understanding of the biology
of different diseases. However, these discoveries have not yet been fully translated into …

Amygdalin-A pharmacological and toxicological review

XY He, LJ Wu, WX Wang, PJ Xie, YH Chen… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Amygdalin is commonly distributed in plants of the
Rosaceae, such as peach, plum, loquat, apple and bayberry, but most notably in the seeds …

The effects of vitamin B on the immune/cytokine network and their involvement in depression

K Mikkelsen, L Stojanovska, M Prakash… - Maturitas, 2017 - Elsevier
Increasing evidence indicates that there are various interactions between the nervous
system and the immune system, and that the immune system plays an important role in the …

Recent updates and future perspectives about amygdalin as a potential anticancer agent: A review

J Shi, Q Chen, M Xu, Q Xia, T Zheng, J Teng… - Cancer …, 2019 - Wiley Online Library
The overall incidence of cancer is increasing in recent years. Despite advances in various
comprehensive treatments, the mortality of advanced malignant tumors remains at a high …

Drug delivery based on stimuli-responsive injectable hydrogels for breast cancer therapy: A review

H Xin, S Naficy - Gels, 2022 - mdpi.com
Breast cancer is the most common and biggest health threat for women. There is an urgent
need to develop novel breast cancer therapies to overcome the shortcomings of …

Guizhi Fuling Wan reduces autophagy of granulosa cell in rats with polycystic ovary syndrome via restoring the PI3K/AKT/mTOR signaling pathway

M Liu, H Zhu, Y Zhu, X Hu - Journal of Ethnopharmacology, 2021 - Elsevier
Abstract Ethnopharmacological relevance Guizhi Fuling Wan (GFW) is a traditional Chinese
medicine used to remove blood stasis and dissipate phlegm for treating gynecological …

Modulation of dysregulated cancer metabolism by plant secondary metabolites: A mechanistic review

S Fakhri, SZ Moradi, MH Farzaei, A Bishayee - Seminars in cancer biology, 2022 - Elsevier
Several signaling pathways and basic metabolites are responsible for the control of
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …

Role of plant-derived active constituents in cancer treatment and their mechanisms of action

AW Khan, M Farooq, M Haseeb, S Choi - Cells, 2022 - mdpi.com
Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …

Evaluation of amygdalin-loaded alginate-chitosan nanoparticles as biocompatible drug delivery carriers for anticancerous efficacy

R Sohail, SR Abbas - International journal of biological macromolecules, 2020 - Elsevier
Amygdalin, despite possessing anticancerous properties, has been viewed as a
controversial choice due to the presence of the cyanide group. Here, we synthesise and …

Advanced research on anti-tumor effects of amygdalin

Z Song, X Xu - Journal of cancer research and therapeutics, 2014 - journals.lww.com
Malignant tumors are the major disease that cause serious damage to human health, and
have been listed as the premier diseases which seriously threatened human health by …