The minimal structural unit of a solid tumor is a single cell or a cellular compartment such as
the nucleus. A closer look inside the cells reveals that there are functional compartments or …

Cancer metastasis requires the invasion of tumor cells into the stroma and the directed
migration of tumor cells through the stroma toward the vasculature and lymphatics where …

Cells undergo a variety of physiological processes, including division, migration and
differentiation, under the influence of endogenous electrical cues, which are generated …

Breast cancer is anticipated to be responsible for almost 40,000 deaths in the USA in 2011.
The current clinical detection techniques suffer from limitations which motivated researchers …

Each year more than 180,000 new cases of breast cancer are diagnosed in women in the
US If cancer is detected when small and local, treatment options are less dangerous …

A two-part hypothesis has been tested, which proposes that (1) prostate cancer cells are
galvanotactic (ie respond to an electric field by moving directionally) and (2) voltagegated …

Cancer may be a disease of geometry: a misregulation of the field of information that
orchestrates individual cells' activities towards normal anatomy. Recent work identified …

The mechanisms by which cancer cells migrate to metastasise are not fully understood.
Breast cancers are accompanied by electrical depolarisation of tumour epithelial cells. The …

As the leading cause of death in cancer, there is an urgent need to develop treatments to
target the dissemination of primary tumor cells to secondary organs, known as metastasis …

Cancer growth interferes with local ionic environments, membrane potentials, and
transepithelial potentials, resulting in small electrical changes in the tumor …