Pathophysiology of human visceral obesity: an update

A Tchernof, JP Després - Physiological reviews, 2013 - journals.physiology.org
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications

E Diamanti-Kandarakis, A Dunaif - Endocrine reviews, 2012 - academic.oup.com
Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic as well as
reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected …

Sex-specific differences in lipid and glucose metabolism

O Varlamov, CL Bethea, CT Roberts Jr - Frontiers in endocrinology, 2015 - frontiersin.org
Energy metabolism in humans is tuned to distinct sex-specific functions that potentially
reflect the unique requirements in females for gestation and lactation, whereas male …

Female mice are protected against high-fat diet induced metabolic syndrome and increase the regulatory T cell population in adipose tissue

US Pettersson, TB Waldén, PO Carlsson, L Jansson… - 2012 - journals.plos.org
Sex differences in obesity-induced complications such as type 2 diabetes have been
reported. The aim of the study was to pinpoint the mechanisms resulting in different outcome …

Adipose organ development and remodeling

S Cinti - Comprehensive Physiology, 2018 - iris.univpm.it
During the last decades, research on adipose tissues has spread in parallel with the
extension of obesity. Several observations converged on the idea that adipose tissues are …

Adipokines as novel biomarkers and regulators of the metabolic syndrome

Y Deng, PE Scherer - Annals of the New York Academy of …, 2010 - Wiley Online Library
Over the past two decades our view of adipose tissue has undergone a dramatic change
from an inert energy storage tissue to an active endocrine organ. Adipose tissue …

The developmental origins of adipose tissue

DC Berry, D Stenesen, D Zeve, JM Graff - Development, 2013 - journals.biologists.com
Adipose tissue is formed at stereotypic times and locations in a diverse array of organisms.
Once formed, the tissue is dynamic, responding to homeostatic and external cues and …

[HTML][HTML] Phenotypic sexual dimorphism in response to dietary fat manipulation in C57BL/6J mice

I Casimiro, ND Stull, SA Tersey, RG Mirmira - Journal of Diabetes and its …, 2021 - Elsevier
Background Obesity and the metabolic syndrome are increasingly prevalent in society and
their complications and response to treatment exhibit sexual dimorphism. Mouse models of …

Prenatal exposure to persistent organic pollutants and childhood obesity: A systematic review and meta‐analysis of human studies

N Stratakis, S Rock, MA La Merrill, M Saez… - Obesity …, 2022 - Wiley Online Library
We conducted a systematic review and meta‐analysis of the associations between prenatal
exposure to persistent organic pollutants (POPs) and childhood obesity. We focused on …

Sex differences in the metabolic syndrome: implications for cardiovascular health in women

AD Pradhan - Clinical chemistry, 2014 - academic.oup.com
BACKGROUND: The metabolic syndrome is a clinical condition characterized by the
presence of multiple interrelated risk factors for type 2 diabetes and cardiovascular disease …