Biomembrane-based nanostructures for cancer targeting and therapy: from synthetic liposomes to natural biomembranes and membrane-vesicles
The translational success of liposomes in chemotherapeutics has already demonstrated the
great potential of biomembrane-based nanostructure in effective drug delivery. Meanwhile …
great potential of biomembrane-based nanostructure in effective drug delivery. Meanwhile …
Photodynamic-based combinatorial cancer therapy strategies: Tuning the properties of nanoplatform according to oncotherapy needs
In recent years, the wide application of photodynamic therapy (PDT) in the field of
biomedicine has proved its significance in cancer treatment. A variety of nanomaterials are …
biomedicine has proved its significance in cancer treatment. A variety of nanomaterials are …
Immunogenic cell death augmented by manganese zinc sulfide nanoparticles for metastatic melanoma immunotherapy
Both T-cell deprivation and insufficient tumor immunogenicity seriously hinder the efficacy of
immune-mediated tumor destruction in melanoma. In this work, an amphiphilic polyethylene …
immune-mediated tumor destruction in melanoma. In this work, an amphiphilic polyethylene …
GSH-responsive nanoprodrug to inhibit glycolysis and alleviate immunosuppression for cancer therapy
X Liu, Y Li, K Wang, Y Chen, M Shi, X Zhang… - Nano Letters, 2021 - ACS Publications
Blocking energy metabolism of cancer cells and simultaneously stimulating the immune
system to perform immune attack are significant for cancer treatment. However, how to …
system to perform immune attack are significant for cancer treatment. However, how to …
Cancer immunogenic cell death via photo-pyroptosis with light-sensitive Indoleamine 2, 3-dioxygenase inhibitor conjugate
Y Lu, F Xu, Y Wang, C Shi, Y Sha, G He, Q Yao, K Shao… - Biomaterials, 2021 - Elsevier
Immune checkpoint blockade (ICB) therapy currently considered as to be effective way to
cure cancer in clinic. However, the insufficient tumor immunogenicity and the …
cure cancer in clinic. However, the insufficient tumor immunogenicity and the …
[HTML][HTML] Lotus seedpod-inspired internal vascularized 3D printed scaffold for bone tissue repair
X Han, M Sun, B Chen, Q Saiding, J Zhang, H Song… - Bioactive materials, 2021 - Elsevier
In the field of bone defect repair, 3D printed scaffolds have the characteristics of
personalized customization and accurate internal structure. However, how to construct a …
personalized customization and accurate internal structure. However, how to construct a …
[HTML][HTML] Temperature sensitive liposome based cancer nanomedicine enables tumour lymph node immune microenvironment remodelling
S Fu, L Chang, S Liu, T Gao, X Sang, Z Zhang… - Nature …, 2023 - nature.com
Targeting tumour immunosuppressive microenvironment is a crucial strategy in
immunotherapy. However, the critical role of the tumour lymph node (LN) immune …
immunotherapy. However, the critical role of the tumour lymph node (LN) immune …
[HTML][HTML] Multifunctional nanoparticle-mediated combining therapy for human diseases
X Li, X Peng, M Zoulikha, GF Boafo, KT Magar… - … and Targeted Therapy, 2024 - nature.com
Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …
disease prevention and treatment. In preclinical investigations, combined effect of certain …
A siRNA-assisted assembly strategy to simultaneously suppress “self” and upregulate “eat-me” signals for nanoenabled chemo-immunotherapy
Effectively activating macrophages that can engulf cancer cells is a promising
immunotherapeutic strategy but remains a major challenge due to the expression of “self” …
immunotherapeutic strategy but remains a major challenge due to the expression of “self” …
[HTML][HTML] Synergistic effect of tumor chemo-immunotherapy induced by leukocyte-hitchhiking thermal-sensitive micelles
J Qi, F Jin, Y You, Y Du, D Liu, X Xu, J Wang… - Nature …, 2021 - nature.com
Some specific chemotherapeutic drugs are able to enhance tumor immunogenicity and
facilitate antitumor immunity by inducing immunogenic cell death (ICD). However, tumor …
facilitate antitumor immunity by inducing immunogenic cell death (ICD). However, tumor …