Catalytic properties and biomedical applications of cerium oxide nanoparticles
Cerium oxide nanoparticles (nanoceria) have shown promise as catalytic antioxidants in the
test tube, cell culture models and animal models of disease. However given the reactivity …
test tube, cell culture models and animal models of disease. However given the reactivity …
Animal models of multiple sclerosis
Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) which involves a complex interaction between immune system and neural …
system (CNS) which involves a complex interaction between immune system and neural …
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation
JK Ryu, MA Petersen, SG Murray, KM Baeten… - Nature …, 2015 - nature.com
Autoimmunity and macrophage recruitment into the central nervous system (CNS) are
critical determinants of neuroinflammatory diseases. However, the mechanisms that drive …
critical determinants of neuroinflammatory diseases. However, the mechanisms that drive …
Synaptopathy connects inflammation and neurodegeneration in multiple sclerosis
G Mandolesi, A Gentile, A Musella… - Nature Reviews …, 2015 - nature.com
Multiple sclerosis (MS) has long been regarded as a chronic inflammatory disease of the
white matter that leads to demyelination and eventually to neurodegeneration. In the past …
white matter that leads to demyelination and eventually to neurodegeneration. In the past …
The neuroprotective functions of transforming growth factor beta proteins
A Dobolyi, C Vincze, G Pál, G Lovas - International journal of molecular …, 2012 - mdpi.com
Transforming growth factor beta (TGF-β) proteins are multifunctional cytokines whose neural
functions are increasingly recognized. The machinery of TGF-β signaling, including the …
functions are increasingly recognized. The machinery of TGF-β signaling, including the …
[HTML][HTML] The multifactorial role of the 3Rs in shifting the harm-benefit analysis in animal models of disease
ML Graham, MJ Prescott - European Journal of Pharmacology, 2015 - Elsevier
Ethics on animal use in science in Western society is based on utilitarianism, weighing the
harms and benefits to the animals involved against those of the intended human …
harms and benefits to the animals involved against those of the intended human …
Neuroprotective effects of estrogens and androgens in CNS inflammation and neurodegeneration
RD Spence, RR Voskuhl - Frontiers in neuroendocrinology, 2012 - Elsevier
Multiple sclerosis (MS) is a disease characterized by inflammation and demyelination.
Currently, the cause of MS is unknown. Experimental autoimmune encephalomyelitis (EAE) …
Currently, the cause of MS is unknown. Experimental autoimmune encephalomyelitis (EAE) …
Modeling neurodegenerative disorders in zebrafish
AA Bashirzade, KN Zabegalov, AD Volgin… - Neuroscience & …, 2022 - Elsevier
Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …
[HTML][HTML] Diversity of reactive astrogliosis in CNS pathology: heterogeneity or plasticity?
AJ Moulson, JW Squair, RJM Franklin… - Frontiers in cellular …, 2021 - frontiersin.org
Astrocytes are essential for the development and homeostatic maintenance of the central
nervous system (CNS). They are also critical players in the CNS injury response during …
nervous system (CNS). They are also critical players in the CNS injury response during …
Bifidobacterium animalis in combination with human origin of Lactobacillus plantarum ameliorate neuroinflammation in experimental model of multiple sclerosis by …
Z Salehipour, D Haghmorad, M Sankian… - Biomedicine & …, 2017 - Elsevier
Abstract Background Multiple Sclerosis (MS) is a chronic inflammatory autoimmune disease
of the central nervous system (CNS). Recent reports have shown that probiotics can induce …
of the central nervous system (CNS). Recent reports have shown that probiotics can induce …