Autoimmune diseases (AID) encompass a diverse array of conditions characterized by
immune system dysregulation, resulting in aberrant responses of B cells and T cells against …

Platelets are clearly central to thrombosis and hemostasis. In addition, more recently,
evidence has emerged for non-hemostatic roles of platelets including inflammatory and …

Multiple sclerosis is a common and frequently disabling neurological disease of young
adults. It is characterised by recurrent areas of focal inflammation (plaques) in the CNS …

MicroRNA (miRNA) are small non-coding RNA molecules about 21–25 nucleotides long.
They control gene regulation by translational repression and cleavage. Several studies have …

The central nervous system (CNS) largely comprises nonregenerating cells, including
neurons and myelin-producing oligodendrocytes, which are particularly vulnerable to …

Experimental models of multiple sclerosis : Current Opinion in Neurology Experimental models
of multiple sclerosis : Current Opinion in Neurology Log in or Register Subscribe to …

Multiple sclerosis (MS) is an autoimmune-mediated degenerative disease of the central
nervous system (CNS) characterized by immune cell infiltration, demyelination and axonal …

Experimental autoimmune encephalomyelitis (EAE) is a spectrum of neurological disorders
in laboratory animals that is used to model multiple sclerosis (MS). However, few agents …

One hallmark of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis
(EAE) is infiltration of leukocytes into the CNS, where chemokines and their receptors play a …

MicroRNAs (miRNAs) have recently emerged as a new class of modulators of gene
expression. miRNAs control protein synthesis by targeting mRNAs for translational …