Myelin oligodendrocyte glycoprotein 35-55 (MOG 35-55)-induced experimental autoimmune encephalomyelitis: a model of chronic multiple sclerosis

S Miyamura, N Matsuo, K Nagayasu, H Shirakawa… - Bio …, 2019 - bio-protocol.org
Multiple sclerosis (MS) is the common demyelinating disease of human central nervous
system. Among mouse models available to study MS, including the cuprizone application …

Local assessment of myelin health in a multiple sclerosis mouse model using a 2D Fourier transform approach

S Bégin, E Bélanger, S Laffray, B Aubé… - Biomedical optics …, 2013 - opg.optica.org
We present an automated two-dimensional Fourier transform (2D-FT) approach to analyze
the local organization of myelinated axons in the spinal cord. Coherent anti-Stokes Raman …

Tolerogenic vaccines for multiple sclerosis

MD Mannie, AD Curtis, II - Human vaccines & immunotherapeutics, 2013 - Taylor & Francis
Tolerogenic vaccines represent a new class of vaccine designed to re-establish
immunological tolerance, restore immune homeostasis, and thereby reverse autoimmune …

Blockade of tumour necrosis factor-α in experimental autoimmune encephalomyelitis reveals differential effects on the antigen-specific immune response and central …

H Batoulis, MS Recks, FO Holland… - Clinical & …, 2014 - academic.oup.com
In various autoimmune diseases, anti-tumour necrosis factor (TNF)-α treatment has been
shown to reduce both clinical disease severity and T helper type 1 (Th1) 1/Th17 responses …

Urinary and plasma metabolomics identify the distinct metabolic profile of disease state in chronic mouse model of multiple sclerosis

J Singh, M Cerghet, LM Poisson, I Datta… - Journal of Neuroimmune …, 2019 - Springer
Identification of non-invasive biomarkers of disease progression in multiple sclerosis (MS) is
critically needed for monitoring the disease progression and for effective therapeutic …

New findings and old controversies in the research of multiple sclerosis and its model experimental autoimmune encephalomyelitis

R Aharoni - Expert review of clinical immunology, 2013 - Taylor & Francis
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS that is
heterogeneous in its clinical manifestation and progression, as well as in its pathological …

[HTML][HTML] Combinatorial effect of metformin and lovastatin impedes T-cell autoimmunity and neurodegeneration in experimental autoimmune encephalomyelitis

AS Paintlia, S Mohan, I Singh - Journal of clinical & cellular …, 2013 - ncbi.nlm.nih.gov
Multiple Sclerosis (MS) is an incurable central nervous system (CNS) demyelinating disease
affecting several million people worldwide. Due to the multifactorial and complex pathology …

The effect of B-cell depletion in the Theiler's model of multiple sclerosis

F Gilli, L Li, SJ Campbell, DC Anthony… - Journal of the …, 2015 - Elsevier
B cell depletion (BCD) is being considered as a treatment for multiple sclerosis (MS), but
there are many uncertainties surrounding the use of this therapy, such as its potential effect …

Multiparametric magnetic resonance imaging for detection of pathological changes in the central nervous system of a mouse model of multiple sclerosis in vivo

AA Althobity, N Khan, CJ Sandrock… - NMR in …, 2023 - Wiley Online Library
Multiple sclerosis (MS) is an autoimmune disease involving demyelination and axonal
damage in the central nervous system (CNS). In this study, we investigated pathological …

Stem cell therapy for cuprizone model of multiple sclerosis focusing on the effectiveness of different injection methods and cell labeling

M Marzban, A Rustamzadeh, A Asghari, Y Terme… - Acta …, 2022 - Elsevier
Multiple Sclerosis (MS) is a chronic and autoimmune disease of the central nervous system
that causes inflammation in the brain and spinal cord, progressive degeneration of central …