Anti-glomerular basement membrane (anti-GBM) disease is a rare life-threatening small-
vessel vasculitis that typically affects the capillaries of kidneys and lungs, with most of …

Antiglomerular basement membrane (anti-GBM) disease is an autoimmune disorder that
mostly presents as raised titers of antibodies against the GBM, rapidly progressive …

Human skin consists of a stratified, cellular epidermis and an underlying dermis of
connective tissue [1–5]. The dermal–epidermal junction is undulating in section; ridges of …

Results: The alpha 3 protein constituent of type IV collagen is thought to be the antigen
implicated in Goodpasture's syndrome, wherein the immune system attacks the basement …

Background: In major depressive disorder (MDD), findings include hyperstable regulation of
brain arousal measured by electroencephalography (EEG) vigilance analysis and …

Autoimmune blistering dermatoses are examples of skin-specific autoimmune disorders that
can sometimes represent the cutaneous manifestation of a multiorgan disease due to …

A detailed appreciation of the development, structure and function of human skin is
fundamental to understanding diseases that originate in or target the skin. Recent advances …

Goodpasture's or anti-glomerular basement membrane (GBM) disease is classically
characterized by the presence of circulating autoantibodies directed against the non …

Basement membrane components are targets of autoimmune attack in diverse diseases that
destroy kidneys, lungs, skin, mucous membranes, joints, and other organs in man. Epitopes …

Atypical anti-GBM disease is characterized by linear immunoglobulin G (IgG) deposition
along the glomerular basement membrane (GBM) without circulating IgG anti-GBM …