Clinical screening for Ph-like ALL and the developing role of TKIs
Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a common
subtype of B-lineage acute lymphoblastic leukemia (B-ALL) with increasing frequency …
subtype of B-lineage acute lymphoblastic leukemia (B-ALL) with increasing frequency …
IKZF1 alterations in acute lymphoblastic leukemia: the good, the bad and the ugly
S Vairy, TH Tran - Blood Reviews, 2020 - Elsevier
Advances in genomics have deepened our understanding of the biology of acute
lymphoblastic leukemia (ALL), defined novel molecular leukemia subtypes, discovered new …
lymphoblastic leukemia (ALL), defined novel molecular leukemia subtypes, discovered new …
[HTML][HTML] Mutated IKZF1 is an independent marker of adverse risk in acute myeloid leukemia
Genetic lesions of IKZF1 are frequent events and well-established markers of adverse risk in
acute lymphoblastic leukemia. However, their function in the pathophysiology and impact on …
acute lymphoblastic leukemia. However, their function in the pathophysiology and impact on …
Role of RNA binding proteins of the Drosophila behavior and human splicing (DBHS) family in health and cancer
T Takeiwa, K Ikeda, K Horie, S Inoue - RNA biology, 2024 - Taylor & Francis
ABSTRACT RNA-binding proteins (RBPs) play crucial roles in the functions and
homoeostasis of various tissues by regulating multiple events of RNA processing including …
homoeostasis of various tissues by regulating multiple events of RNA processing including …
[HTML][HTML] Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis
L Huang, X An, Y Zhu, K Zhang, L Xiao, X Yao… - Cell Communication and …, 2022 - Springer
Background B-cell acute lymphoblastic leukemia (B-ALL) comprises over 85% of all acute
lymphoblastic leukemia (ALL) cases and is the most common childhood malignancy …
lymphoblastic leukemia (ALL) cases and is the most common childhood malignancy …
Role of matrix metalloproteinase MMP-2, MMP-9 and tissue inhibitor of metalloproteinase (TIMP-1) in the clinical progression of pediatric acute lymphoblastic …
M Saleh, M Khalil, MS Abdellateif, E Ebeid… - …, 2021 - Taylor & Francis
ABSTRACT Background Matrix metalloproteinases (MMPs) play a crucial role in cancer
progression and metastasis, however their role in pediatric Acute lymphoblastic leukemia …
progression and metastasis, however their role in pediatric Acute lymphoblastic leukemia …
[HTML][HTML] Genomic Analyses of Pediatric Acute Lymphoblastic Leukemia Ph+ and Ph-Like—Recent Progress in Treatment
A Kaczmarska, P Śliwa, J Zawitkowska… - International Journal of …, 2021 - mdpi.com
Pediatric acute lymphoblastic leukemia (ALL) with t (9; 22)(q34; q11. 2) is a very rare
malignancy in children. Approximately 3–5% of pediatric ALL patients present with the …
malignancy in children. Approximately 3–5% of pediatric ALL patients present with the …
Updates on lymphoblastic leukemia/lymphoma classification and minimal/measurable residual disease analysis
AE Kovach, BL Wood - Seminars in Diagnostic Pathology, 2023 - Elsevier
Lymphoblastic leukemia/lymphoma (ALL/LBL), especially certain subtypes, continues to
confer morbidity and mortality despite significant therapeutic advances. The pathologic …
confer morbidity and mortality despite significant therapeutic advances. The pathologic …
Has Ph-like ALL superseded Ph+ ALL as the least favorable subtype?
Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a subset of
high-risk B-ALL associated with high relapse risk and inferior clinical outcomes across the …
high-risk B-ALL associated with high relapse risk and inferior clinical outcomes across the …
SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia
Abstract Philadelphia-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk
subtype of B-cell ALL characterized by a gene expression profile resembling Philadelphia …
subtype of B-cell ALL characterized by a gene expression profile resembling Philadelphia …