Summary Double-stranded (ds) DNA, DNA-or RNA-associated nucleoproteins are the
primary autoimmune targets in SLE, yet their relative inability to trigger similar autoimmune …

Silicosis is one of the oldest occupational diseases known to man. It is an irreversible fibrotic
lung disease caused by inhalation of crystalline silicon dioxide or silica. In spite of optimal …

Synthetic oligodeoxynucleotides (ODN) capable of “neutralizing” or “inhibiting” immune
responses have been described. This review will focus on the properties of …

In order to evaluate the role of taurine on the oxidative stress mediated by NADPH oxidase
in Streptococcus uberis-induced (S. uberis) mastitis, rats were administered daily (per os) …

Synthetic oligonucleotides (ODNs) containing unmethylated 'CpG motifs' stimulate the innate
immune system to produce cytokines, chemokines, and polyreactive antibodies. CpG ODNs …

Silicosis is an occupational disease caused by inhalation of silica dust, which is hallmarked
by progressive pulmonary fibrosis associated with poor prognosis. Wnt/β-catenin signaling …

We previously reported the strong immunostimulatory effects of a CpG oligodeoxynucleotide
(ODN), designated MsST, from the lacZ gene of Streptococcus (S.) thermophilus …

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We designed class I/II hybrid inhibitory oligodeoxynucleotides (iODNs), called iSG, and
found that the sequence 5′-TTAGGG-3′, which has a six-base loop head structure, and a …

Type I allergic diseases, such as allergic rhinitis and asthma, depend on allergen-induced T-
helper type 2 (Th2) cells and IgE-secreting plasma cells. Fortunately, this harmful immune …