Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …
[HTML][HTML] Epithelial–Mesenchymal Transition Mechanisms in Chronic Airway Diseases: A Common Process to Target?
A Mottais, L Riberi, A Falco, S Soccal, S Gohy… - International journal of …, 2023 - mdpi.com
Epithelial-to-mesenchymal transition (EMT) is a reversible process, in which epithelial cells
lose their epithelial traits and acquire a mesenchymal phenotype. This transformation has …
lose their epithelial traits and acquire a mesenchymal phenotype. This transformation has …
Assessing the efficacy of fenugreek saponin nanoparticles in attenuating nicotine-induced hepatotoxicity in male rats
KA Hamed, SA El-Fiky, AM Gawish… - ACS …, 2023 - ACS Publications
During smoking, nicotine, the most bountiful compound in cigarettes, is absorbed into the
body by the lungs and quickly metabolized in the liver, causing three major adverse impacts …
body by the lungs and quickly metabolized in the liver, causing three major adverse impacts …
A Conformable Organic Electronic Device for Monitoring Epithelial Integrity at the Air Liquid Interface
Air liquid interfaced (ALI) epithelial barriers are essential for homeostatic functions such as
nutrient transport and immunological protection. Dysfunction of such barriers are implicated …
nutrient transport and immunological protection. Dysfunction of such barriers are implicated …
[HTML][HTML] Electronic cigarette exposure increases the severity of influenza a virus infection via TRAIL dysregulation in human precision-cut lung slices
The use of electronic nicotine dispensing systems (ENDS), also known as electronic
cigarettes (ECs), is common among adolescents and young adults with limited knowledge …
cigarettes (ECs), is common among adolescents and young adults with limited knowledge …
[HTML][HTML] Sodium pyruvate exerts protective effects against cigarette smoke extract-induced ferroptosis in alveolar and bronchial epithelial cells through the GPX4/Nrf2 …
Z Zhao, Z Xu, J Chang, L He, Z Zhang, X Song… - Journal of …, 2023 - Springer
Background Ferroptosis in alveolar and bronchial epithelial cells is one of the main
mechanisms underlying the development of chronic obstructive pulmonary disease (COPD) …
mechanisms underlying the development of chronic obstructive pulmonary disease (COPD) …
Epithelial–mesenchymal transition changes in nonsmall cell lung cancer patients with early COPD
Background Epithelial–mesenchymal transition (EMT) might be central to lung cancer
development in smokers and COPD. We illustrate EMT changes in a broader demographic …
development in smokers and COPD. We illustrate EMT changes in a broader demographic …
Efficacy and Mechanisms of Natural Products as Therapeutic Interventions for Chronic Respiratory Diseases
F Jin, P Fan, Y Wu, Q Yang, J Li, H Liu - The American Journal of …, 2024 - World Scientific
Chronic respiratory diseases are long-term conditions affecting the airways and other lung
components that are characterized by a high prevalence, disability rate, and mortality rate …
components that are characterized by a high prevalence, disability rate, and mortality rate …
MMPs as potential molecular target in epithelial-to-mesenchymal transition driven COPD progression
Chronic obstructive pulmonary disease (COPD) is the third leading cause of mortality
globally and the risk of developing lung cancer is six times greater in individuals with COPD …
globally and the risk of developing lung cancer is six times greater in individuals with COPD …
Fecal microbiome extract downregulates the expression of key proteins at the interface between airway remodelling and lung cancer pathogenesis in vitro
Lung cancer (LC) is the leading cause of cancer-related mortality, and it is caused by many
factors including cigarette smoking. Despite numerous treatment strategies for LC, its five …
factors including cigarette smoking. Despite numerous treatment strategies for LC, its five …