The Parkinson progression marker initiative (PPMI)

K Marek, D Jennings, S Lasch, A Siderowf… - Progress in …, 2011 - Elsevier
The Parkinson Progression Marker Initiative (PPMI) is a comprehensive observational,
international, multi-center study designed to identify PD progression biomarkers both to …

Biosensor technology: recent advances in threat agent detection and medicine

J Kirsch, C Siltanen, Q Zhou, A Revzin… - Chemical Society …, 2013 - pubs.rsc.org
Biosensors are of great significance because of their capability to resolve a potentially large
number of analytical problems and challenges in very diverse areas such as defense …

Review on alzheimer disease detection methods: Automatic pipelines and machine learning techniques

A Shukla, R Tiwari, S Tiwari - Sci, 2023 - mdpi.com
Alzheimer's Disease (AD) is becoming increasingly prevalent across the globe, and various
diagnostic and detection methods have been developed in recent years. Several techniques …

Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

M Thambisetty, A Simmons… - Archives of general …, 2010 - jamanetwork.com
Context Blood-based analytes may be indicators of pathological processes in Alzheimer
disease (AD). Objective To identify plasma proteins associated with AD pathology using a …

Biomarkers in Parkinson's disease (recent update)

S Sharma, CS Moon, A Khogali, A Haidous… - Neurochemistry …, 2013 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorder mostly
affecting the aging population over sixty. Cardinal symptoms including, tremors, muscle …

Neuronal dark matter: the emerging role of microRNAs in neurodegeneration

EF Goodall, PR Heath, O Bandmann, J Kirby… - Frontiers in cellular …, 2013 - frontiersin.org
MicroRNAs (miRNAs) are small, abundant RNA molecules that constitute part of the cell's
non-coding RNA “dark matter.” In recent years, the discovery of miRNAs has revolutionised …

Biomarkers in multiple sclerosis

A Paul, M Comabella, R Gandhi - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disease with a complex
clinical course characterized by inflammation, demyelination, and axonal degeneration …

Neurodegenerative disorders of alzheimer, parkinsonism, amyotrophic lateral sclerosis and multiple sclerosis: an early diagnostic approach for precision treatment

N Pathak, SK Vimal, I Tandon, L Agrawal… - Metabolic Brain …, 2021 - Springer
Neurodegenerative diseases (NDs) are characterised by progressive dysfunction of
synapses, neurons, glial cells and their networks. Neurodegenerative diseases can be …

Blood-based biomarkers for Parkinson's disease

LM Chahine, MB Stern, A Chen-Plotkin - Parkinsonism & related disorders, 2014 - Elsevier
There is a pressing need for biomarkers to diagnose Parkinson's disease (PD), assess
disease severity, and prognosticate course. Various types of biologic specimens are …

Alzheimer disease pathology and the cerebrospinal fluid proteome

L Dayon, A Núñez Galindo, J Wojcik… - Alzheimer's research & …, 2018 - Springer
Background Altered proteome profiles have been reported in both postmortem brain tissues
and body fluids of subjects with Alzheimer disease (AD), but their broad relationships with …