Akkermansia muciniphila is a Gram-negative anaerobic mucus-layer-degrading bacterium
that colonizes the intestinal mucosa of humans and rodents. Metagenomic data have shown …

A substantial body of literature has provided evidence for the role of gut microbiota in
metabolic diseases including type 2 diabetes. However, reports vary regarding the …

Background Recently, the hallmarks of aging were updated to include dysbiosis, disabled
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …

The microbiome has received increasing attention over the last 15 years. Although gut
microbes have been explored for several decades, investigations of the role of …

Obesity and its metabolic syndrome, including liver disorders and type 2 diabetes, are a
worldwide epidemic and are intimately linked to diet. The gut microbiota interaction has …

IFNγ is a cytokine with important roles in tissue homeostasis, immune and inflammatory
responses and tumour immunosurveillance. Signalling by the IFNγ receptor activates the …

Metabolic disorders associated with obesity and cardiometabolic disorders are worldwide
epidemic. Among the different environmental factors, the gut microbiota is now considered …

Intestinal adaptive immune responses influence host health, yet only a few intestinal
bacteria species that induce cognate adaptive immune responses during homeostasis have …

Parkinson's disease (PD) is the second most common neurodegenerative disease
characterized by motor dysfunction. Growing evidence has demonstrated that gut dysbiosis …

Taxonomic and functional changes to the composition of the gut microbiome have been
implicated in multiple human diseases. Recent microbiome genome-wide association …