Microbial production of L-methionine and its precursors using systems metabolic engineering
M Cai, Z Liu, Z Zhao, H Wu, M Xu, Z Rao - Biotechnology Advances, 2023 - Elsevier
L-methionine is an essential amino acid with versatile applications in food, feed, cosmetics
and pharmaceuticals. At present, the production of L-methionine mainly relies on chemical …
and pharmaceuticals. At present, the production of L-methionine mainly relies on chemical …
[HTML][HTML] CRISPR-based gene editing technology and its application in microbial engineering
J Wei, Y Li - Engineering Microbiology, 2023 - Elsevier
Gene editing technology involves the modification of a specific target gene to obtain a new
function or phenotype. Recent advances in clustered regularly interspaced short palindromic …
function or phenotype. Recent advances in clustered regularly interspaced short palindromic …
Dual-channel glycolysis balances cofactor supply for l-homoserine biosynthesis in Corynebacterium glutamicum
Abstract l-Homoserine is an important platform compound that is widely used to produce
many valuable bio-based products, but production of l-homoserine in Corynebacterium …
many valuable bio-based products, but production of l-homoserine in Corynebacterium …
High-Level Production of l-Methionine by Dynamic Deregulation of Metabolism with Engineered Nonauxotroph Escherichia coli
K Niu, Q Fu, ZL Mei, LR Ge, AQ Guan, ZQ Liu… - ACS Synthetic …, 2023 - ACS Publications
l-Methionine is the only sulfur-containing amino acid among the essential amino acids, and
it is mainly produced by the chemical method in industry so far. The fermentation production …
it is mainly produced by the chemical method in industry so far. The fermentation production …
Progress in research on the biosynthesis of 1, 2, 4-butanetriol by engineered microbes
X Ma, C Sun, M Xian, J Guo, R Zhang - World Journal of Microbiology and …, 2024 - Springer
butanetriol (BT) is a polyol with unique chemical properties, which has a stereocenter and
can be divided into D-BT (the S-enantiomer) and L-BT (the R-enantiomer). BT can be used …
can be divided into D-BT (the S-enantiomer) and L-BT (the R-enantiomer). BT can be used …
Advances in Synthetic Biology Techniques and Industrial Applications of Corynebacterium glutamicum
Y Wang, Q Wang, A Sha, K Ren, M Hu, M Xu, X Zhang… - Fermentation, 2023 - mdpi.com
Corynebacterium glutamicum is a Gram-positive bacterium (non-spore-forming) that has
been wildly used for amino acid production. Due to its stable protein secretion, low …
been wildly used for amino acid production. Due to its stable protein secretion, low …