[HTML][HTML] Pathogenetic mechanisms in gastric cancer

J Shi, YP Qu, P Hou - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Gastric cancer (GC) is a major public health issue as the fourth most common cancer and
the second leading cause of cancer-related death. Recent advances have improved our …

[HTML][HTML] Genomic and genetic alterations influence the progression of gastric cancer

S Nobili, L Bruno, I Landini, C Napoli… - World journal of …, 2011 - ncbi.nlm.nih.gov
Gastric cancer is one of the leading causes of cancer-related deaths worldwide, although
the incidence has gradually decreased in many Western countries. Two main gastric cancer …

miR-449 inhibits cell proliferation and is down-regulated in gastric cancer

T Bou Kheir, E Futoma-Kazmierczak, A Jacobsen… - Molecular cancer, 2011 - Springer
Background Gastric cancer is the fourth most common cancer in the world and the second
most prevalent cause of cancer related death. The development of gastric cancer is mainly …

PPARgamma inhibits hepatocellular carcinoma metastases in vitro and in mice

B Shen, ESH Chu, G Zhao, K Man, CW Wu… - British journal of …, 2012 - nature.com
Background: We have previously demonstrated that peroxisome proliferator-activated
receptor (PPARγ) activation inhibits hepatocarcinogenesis. We aim to investigate the effect …

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells

K Hütz, R Mejías-Luque, K Farsakova, M Ogris… - …, 2014 - academic.oup.com
Gastric cancer (GC) is still one of the most common causes of cancer-related death
worldwide, which is mainly attributable to late diagnosis and poor treatment options …

[HTML][HTML] The role and clinical implications of the retinoblastoma (RB)-E2F pathway in gastric cancer

T Wu, L Wu - Frontiers in Oncology, 2021 - frontiersin.org
Gastric cancer is the most common malignant tumor in the digestive tract, with very high
morbidity and mortality in developing countries. The pathogenesis of gastric cancer is a …

Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine

JD Holbrook, JS Parker, KT Gallagher… - Journal of translational …, 2011 - Springer
Background Globally, gastric cancer is the second most common cause of cancer-related
death, with the majority of the health burden borne by economically less-developed …

SATB1 is an independent prognostic marker for gastric cancer in a Chinese population

X Lu, C Cheng, S Zhu, YUN Yang… - Oncology …, 2010 - spandidos-publications.com
Special AT-rich sequence binding protein 1 (SATB1), a new type of gene regulator, has
been reported to express in various human cancers and may associate with the malignant …

[HTML][HTML] TFAP4 promotes hepatocellular carcinoma invasion and metastasis via activating the PI3K/AKT signaling pathway

T Huang, QF Chen, BY Chang, LJ Shen, W Li… - Disease …, 2019 - hindawi.com
Transcription factor activating enhancer binding protein 4 (TFAP4) is established as a
regulator of human cancer genesis and progression. Overexpression of TFAP4 indicates …

TNF‐α's effects on proliferation and apoptosis in human mesenchymal stem cells depend on RUNX2 expression

O Ghali, C Chauveau, P Hardouin… - Journal of Bone and …, 2010 - academic.oup.com
RUNX2 is a bone‐specific transcription factor that plays a critical role in prenatal bone
formation and postnatal bone development. It regulates the expression of genes that are …