The zinc finger proteins make up a significant part of the proteome and perform a huge
variety of functions in the cell. The CCCH-type zinc finger proteins have gained attention due …

Innate immunity is the frontline of defense against infections and tissue damage. It is a fast
and semi-specific response involving a myriad of processes essential for protecting the …

Abstract Human (Hs) Roquin1 and Roquin2 are RNA-binding proteins that promote mRNA
target degradation through the recruitment of the CCR4-NOT deadenylase complex and are …

Discovery of Small-Molecule Modulators of Protein–RNA Interactions by Fluorescence
Intensity-Based Binding Assay | SpringerLink Skip to main content Advertisement SpringerLink …

Peptidylarginine deiminases (PADs) are phylogenetically conserved calcium-dependent
enzymes which post-translationally convert arginine into citrulline in target proteins in an …

With the development of liver surgery, ischemia–reperfusion (IR) injury has received
increasing attention. Roquin-1 has been shown to play an important role in innate immune …

Post-transcriptional gene regulation controls the amount of protein produced from a specific
mRNA by altering both its decay and translation rates. Such regulation is primarily achieved …

Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive peripheral T-cell lymphoma
driven by a pool of neoplastic cells originating from T follicular helper (Tfh) cells and …

Lupus nephritis (LN) is a type of immunological complex glomerulonephritis characterized
by chronic renal inflammation which is exacerbated by infiltrating leukocytes and fueled by a …

Sepsis-associated acute liver injury (SALI) is an independent risk for sepsis-induced death
orchestrated by innate and adaptive immune responses. Here, we found that Roquin-1 was …